ABC Transporter Function and Regulation at the Blood–Spinal Cord Barrier

We present here an initial characterization of ATP binding cassette (ABC) transporter function and regulation at the blood–spinal cord barrier. We isolated capillaries from rat spinal cords and studied transport function using a confocal microscopy-based assay and protein expression using western bl...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of cerebral blood flow and metabolism 2012-08, Vol.32 (8), p.1559-1566
Hauptverfasser:	Campos, Christopher R, Schröter, Christian, Wang, Xueqian, Miller, David S
Format:	Artikel
Sprache:	eng
Schlagworte:	ABC transporter Animals Arterial hypertension. Arterial hypotension Aryl hydrocarbon receptors ATP ATP Binding Cassette Transporter, Sub-Family B - genetics ATP Binding Cassette Transporter, Sub-Family B - metabolism ATP Binding Cassette Transporter, Sub-Family G, Member 2 ATP-Binding Cassette Transporters - genetics ATP-Binding Cassette Transporters - metabolism Biological and medical sciences Biological Transport Blood and lymphatic vessels Blood-brain barrier Blood-Brain Barrier - metabolism Blotting, Western Brain Capillaries Capillaries - metabolism Cardiology. Vascular system Cell Membrane - metabolism Cerebral blood flow Clinical manifestations. Epidemiology. Investigative techniques. Etiology Dioxin Electrophoretic Mobility Shift Assay Ligands Male Medical sciences Mice Mice, Knockout Microscopy, Confocal Multidrug resistance Neurology Original P-Glycoprotein Polychlorinated Dibenzodioxins - pharmacokinetics Protein transport Rats Rats, Sprague-Dawley Spinal cord Spinal Cord - blood supply Spinal Cord - metabolism Vascular diseases and vascular malformations of the nervous system Western blotting Xenobiotics - pharmacokinetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!