Temporal Lobe Epilepsy after Refractory Status Epilepticus: An Illustrative Case and Review of the Literature

New onset refractory status epilepticus (NORSE) is a relatively newly defined disease entity, where otherwise healthy individuals develop unrelenting seizures that do not respond to conventional anticonvulsant therapy and may require months of therapy with anesthetic drugs. We have described a case...

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Veröffentlicht in:Epilepsy Research and Treatment 2012-01, Vol.2012 (2012), p.119-124
Hauptverfasser: Gordon Boyd, J., Young, G. Bryan, Debicki, Derek B.
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Young, G. Bryan
Debicki, Derek B.
description New onset refractory status epilepticus (NORSE) is a relatively newly defined disease entity, where otherwise healthy individuals develop unrelenting seizures that do not respond to conventional anticonvulsant therapy and may require months of therapy with anesthetic drugs. We have described a case of NORSE who subsequently developed mesial temporal lobe sclerosis (MTS) and recurrent temporal lobe seizures. We discuss the possible pathophysiological mechanisms by which refractory seizures may contribute to the development of temporal lobe epilepsy (TLE).
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title Temporal Lobe Epilepsy after Refractory Status Epilepticus: An Illustrative Case and Review of the Literature
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