Darwinian medicine: applications of evolutionary biology for veterinarians
Every medical phenomenon has both a mechanistic explanation and an evolutionary explanation. Veterinarians are accustomed to dealing with the mechanistic, the "what" or the "how", of various disease conditions, and applying treatment accordingly. Darwinian medicine is a field tha...
Gespeichert in:
| Veröffentlicht in: | Canadian veterinary journal 2002-07, Vol.43 (7), p.556-559 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 559 |
|---|---|
| container_issue | 7 |
| container_start_page | 556 |
| container_title | Canadian veterinary journal |
| container_volume | 43 |
| creator | LeGrand, E.K Brown, C.C |
| description | Every medical phenomenon has both a mechanistic explanation and an evolutionary explanation. Veterinarians are accustomed to dealing with the mechanistic, the "what" or the "how", of various disease conditions, and applying treatment accordingly. Darwinian medicine is a field that addresses the evolutionary explanation, the "why" for various medical conditions. This review focuses on these Darwinian explanations and is divided into 4 main categories--host defenses, virulence, genetic conflict, and incomplete adaptation to a changing environment. Each of these areas is reviewed, with examples of evolutionary reasons for disease conditions. Consideration of adaptationist reasons for many of these disease phenomena should make veterinarians better clinicians, educators, and researchers. |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_341948</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>71934347</sourcerecordid><originalsourceid>FETCH-LOGICAL-f285t-6eedde44a7b5123d319f8cc4c293050cceaa44e214adb8e51934fb40790a16423</originalsourceid><addsrcrecordid>eNpVUMtOwzAQzAFES-EXwCdukfzKC4kDKm9V4gA9WxtnU4zcONhJUf8eoxYEp9XuzOyM5iCZUkrLNONlPkmOQ3inlFcsp0fJhHHGM1bRafJ0A_7TdAY6ssbGaNPhJYG-t0bDYFwXiGsJbpwdvzfwW1IbZ91qS1rnyQYH9Caeoz6cJIct2ICn-zlLlne3r_OHdPF8_zi_XqQtL7MhzRGbBqWEos4YF41gVVtqLTWvBM2o1gggJXImoalLjDGFbGtJi4oCyyUXs-Rq97cf65hZYzd4sKr3Zh3zKQdG_Uc686ZWbqOEZJUso_5ir_fuY8QwqLUJGq2FDt0YVPHtKGQRiWd_jX4dftqLhPMdoQWnYOVNUMsXTpmIRfOyEFx8AcqedmI</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>71934347</pqid></control><display><type>article</type><title>Darwinian medicine: applications of evolutionary biology for veterinarians</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><creator>LeGrand, E.K ; Brown, C.C</creator><creatorcontrib>LeGrand, E.K ; Brown, C.C</creatorcontrib><description>Every medical phenomenon has both a mechanistic explanation and an evolutionary explanation. Veterinarians are accustomed to dealing with the mechanistic, the "what" or the "how", of various disease conditions, and applying treatment accordingly. Darwinian medicine is a field that addresses the evolutionary explanation, the "why" for various medical conditions. This review focuses on these Darwinian explanations and is divided into 4 main categories--host defenses, virulence, genetic conflict, and incomplete adaptation to a changing environment. Each of these areas is reviewed, with examples of evolutionary reasons for disease conditions. Consideration of adaptationist reasons for many of these disease phenomena should make veterinarians better clinicians, educators, and researchers.</description><identifier>ISSN: 0008-5286</identifier><identifier>PMID: 12125190</identifier><language>eng</language><publisher>Canada</publisher><subject>adaptation ; Adaptation, Biological ; Adaptation, Physiological - genetics ; Animals ; Biological Evolution ; defense mechanisms ; Environment ; evolution ; evolutionary medicine ; genetics ; Genetics, Medical ; Immunity - genetics ; Selection, Genetic ; veterinarians ; veterinary medicine ; Virulence</subject><ispartof>Canadian veterinary journal, 2002-07, Vol.43 (7), p.556-559</ispartof><rights>Copyright and/or publishing rights held by the Canadian Veterinary Medical Association</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC341948/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC341948/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12125190$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>LeGrand, E.K</creatorcontrib><creatorcontrib>Brown, C.C</creatorcontrib><title>Darwinian medicine: applications of evolutionary biology for veterinarians</title><title>Canadian veterinary journal</title><addtitle>Can Vet J</addtitle><description>Every medical phenomenon has both a mechanistic explanation and an evolutionary explanation. Veterinarians are accustomed to dealing with the mechanistic, the "what" or the "how", of various disease conditions, and applying treatment accordingly. Darwinian medicine is a field that addresses the evolutionary explanation, the "why" for various medical conditions. This review focuses on these Darwinian explanations and is divided into 4 main categories--host defenses, virulence, genetic conflict, and incomplete adaptation to a changing environment. Each of these areas is reviewed, with examples of evolutionary reasons for disease conditions. Consideration of adaptationist reasons for many of these disease phenomena should make veterinarians better clinicians, educators, and researchers.</description><subject>adaptation</subject><subject>Adaptation, Biological</subject><subject>Adaptation, Physiological - genetics</subject><subject>Animals</subject><subject>Biological Evolution</subject><subject>defense mechanisms</subject><subject>Environment</subject><subject>evolution</subject><subject>evolutionary medicine</subject><subject>genetics</subject><subject>Genetics, Medical</subject><subject>Immunity - genetics</subject><subject>Selection, Genetic</subject><subject>veterinarians</subject><subject>veterinary medicine</subject><subject>Virulence</subject><issn>0008-5286</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVUMtOwzAQzAFES-EXwCdukfzKC4kDKm9V4gA9WxtnU4zcONhJUf8eoxYEp9XuzOyM5iCZUkrLNONlPkmOQ3inlFcsp0fJhHHGM1bRafJ0A_7TdAY6ssbGaNPhJYG-t0bDYFwXiGsJbpwdvzfwW1IbZ91qS1rnyQYH9Caeoz6cJIct2ICn-zlLlne3r_OHdPF8_zi_XqQtL7MhzRGbBqWEos4YF41gVVtqLTWvBM2o1gggJXImoalLjDGFbGtJi4oCyyUXs-Rq97cf65hZYzd4sKr3Zh3zKQdG_Uc686ZWbqOEZJUso_5ir_fuY8QwqLUJGq2FDt0YVPHtKGQRiWd_jX4dftqLhPMdoQWnYOVNUMsXTpmIRfOyEFx8AcqedmI</recordid><startdate>20020701</startdate><enddate>20020701</enddate><creator>LeGrand, E.K</creator><creator>Brown, C.C</creator><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20020701</creationdate><title>Darwinian medicine: applications of evolutionary biology for veterinarians</title><author>LeGrand, E.K ; Brown, C.C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-f285t-6eedde44a7b5123d319f8cc4c293050cceaa44e214adb8e51934fb40790a16423</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>adaptation</topic><topic>Adaptation, Biological</topic><topic>Adaptation, Physiological - genetics</topic><topic>Animals</topic><topic>Biological Evolution</topic><topic>defense mechanisms</topic><topic>Environment</topic><topic>evolution</topic><topic>evolutionary medicine</topic><topic>genetics</topic><topic>Genetics, Medical</topic><topic>Immunity - genetics</topic><topic>Selection, Genetic</topic><topic>veterinarians</topic><topic>veterinary medicine</topic><topic>Virulence</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>LeGrand, E.K</creatorcontrib><creatorcontrib>Brown, C.C</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Canadian veterinary journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>LeGrand, E.K</au><au>Brown, C.C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Darwinian medicine: applications of evolutionary biology for veterinarians</atitle><jtitle>Canadian veterinary journal</jtitle><addtitle>Can Vet J</addtitle><date>2002-07-01</date><risdate>2002</risdate><volume>43</volume><issue>7</issue><spage>556</spage><epage>559</epage><pages>556-559</pages><issn>0008-5286</issn><abstract>Every medical phenomenon has both a mechanistic explanation and an evolutionary explanation. Veterinarians are accustomed to dealing with the mechanistic, the "what" or the "how", of various disease conditions, and applying treatment accordingly. Darwinian medicine is a field that addresses the evolutionary explanation, the "why" for various medical conditions. This review focuses on these Darwinian explanations and is divided into 4 main categories--host defenses, virulence, genetic conflict, and incomplete adaptation to a changing environment. Each of these areas is reviewed, with examples of evolutionary reasons for disease conditions. Consideration of adaptationist reasons for many of these disease phenomena should make veterinarians better clinicians, educators, and researchers.</abstract><cop>Canada</cop><pmid>12125190</pmid><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0008-5286 |
| ispartof | Canadian veterinary journal, 2002-07, Vol.43 (7), p.556-559 |
| issn | 0008-5286 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_341948 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | adaptation Adaptation, Biological Adaptation, Physiological - genetics Animals Biological Evolution defense mechanisms Environment evolution evolutionary medicine genetics Genetics, Medical Immunity - genetics Selection, Genetic veterinarians veterinary medicine Virulence |
| title | Darwinian medicine: applications of evolutionary biology for veterinarians |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T15%3A37%3A34IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Darwinian%20medicine:%20applications%20of%20evolutionary%20biology%20for%20veterinarians&rft.jtitle=Canadian%20veterinary%20journal&rft.au=LeGrand,%20E.K&rft.date=2002-07-01&rft.volume=43&rft.issue=7&rft.spage=556&rft.epage=559&rft.pages=556-559&rft.issn=0008-5286&rft_id=info:doi/&rft_dat=%3Cproquest_pubme%3E71934347%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=71934347&rft_id=info:pmid/12125190&rfr_iscdi=true |