Sample size and power analysis for sparse signal recovery in genome-wide association studies

Genome-wide association studies have successfully identified hundreds of novel genetic variants associated with many complex human diseases. However, there is a lack of rigorous work on evaluating the statistical power for identifying these variants. In this paper, we consider sparse signal identifi...

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Veröffentlicht in:Biometrika 2011-06, Vol.98 (2), p.273-290
Hauptverfasser: XIE, JICHUN, CAI, T. TONY, LI, HONGZHE
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Sprache:eng
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