Tetraploid cells from cytokinesis failure induce aneuploidy and spontaneous transformation of mouse ovarian surface epithelial cells

Most ovarian cancers originate from the ovarian surface epithelium and are characterized by aneuploid karyotypes. Aneuploidy, a consequence of chromosome instability, is an early event during the development of ovarian cancers. However, how aneuploid cells are evolved from normal diploid cells in ov...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cell cycle (Georgetown, Tex.) Tex.), 2012-08, Vol.11 (15), p.2864-2875
Hauptverfasser:	Lv, Lei, Zhang, Tianwei, Yi, Qiyi, Huang, Yun, Wang, Zheng, Hou, Heli, Zhang, Huan, Zheng, Wei, Hao, Qiaomei, Guo, Zongyou, Cooke, Howard J., Shi, Qinghua
Format:	Artikel
Sprache:	eng
Schlagworte:	Aneuploidy Animals Binding Biology Bioscience Calcium Cancer Cell Cell Line Cell Transformation, Neoplastic - genetics chromosome mis-segregation Chromosome Segregation Cycle Cytokinesis cytokinesis failure Epithelial Cells Female In Situ Hybridization, Fluorescence Landes Mice Mice, Inbred C57BL Mitosis Organogenesis ovarian cancer Ovarian Neoplasms - genetics Ovarian Neoplasms - metabolism Ovarian Neoplasms - pathology Ovary - metabolism Ovary - pathology Proteins tetraploid cells Tetraploidy
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!