A new regulator of osteoclastogenesis: Estrogen response element–binding protein in bone

The heterogeneous nuclear ribonucleoprotein (hnRNP)–like estrogen response element–binding protein (ERE‐BP) competes with estrogen receptor α (ERα) for occupancy of estrogen response elements (EREs). Here we report that ERE‐BP potently stimulates osteoclastogenesis. ERE‐BP mRNA and protein were foun...

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Veröffentlicht in:	Journal of bone and mineral research 2011-10, Vol.26 (10), p.2537-2547
Hauptverfasser:	Chen, Hong, Gilbert, Linda C, Lu, X, Liu, Zhaofan, You, Shaojin, Weitzmann, M Neale, Nanes, Mark S, Adams, John
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Biological and medical sciences BONE Bone and Bones - metabolism Cell Differentiation Coculture Techniques DNA Primers ESTROGEN Estrogens - physiology Fundamental and applied biological sciences. Psychology hnRNP Mice Mice, Inbred C57BL OSTEOCLAST OSTEOCLASTOGENESIS Osteoclasts - cytology Promoter Regions, Genetic RANK Ligand - genetics RANK Ligand - metabolism RANKL Real-Time Polymerase Chain Reaction Skeleton and joints Vertebrates: osteoarticular system, musculoskeletal system
Online-Zugang:	Volltext
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