A very high amylase can be benign in paediatric Crohn’s disease

A 12.5-year-old boy with Crohn’s disease with abdominal pain had a raised amylase of 1835 IU/l with normal lipase levels. Ultrasound showed no evidence of inflammation of pancreas. The amylase to creatinine clearance ratio, was 0.8% (reference interval 2%–5%; >6% consistent with acute pancreatiti...

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Veröffentlicht in:	BMJ case reports 2012-07, Vol.2012 (jul09 1), p.bcr0220125917-bcr0220125917
Hauptverfasser:	Venkataraman, Devasmitha, Howarth, Lucy, Beattie, Robert Mark, Afzal, Nadeem Ahmad
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdomen Amylases - blood Binding sites Biomarkers - blood Celiac disease Child Crohn Disease - diagnosis Crohn Disease - enzymology Crohn's disease Diagnosis, Differential Europe (West) HIV Human immunodeficiency virus Humans Immunoglobulins Inflammation Inflammatory bowel disease Lymphoma Male Mortality Pancreas Pancreatitis, Acute Necrotizing - diagnosis Plasma Reminder of Important Clinical Lesson Ultrasonic imaging White
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Beschreibung
Zusammenfassung:	A 12.5-year-old boy with Crohn’s disease with abdominal pain had a raised amylase of 1835 IU/l with normal lipase levels. Ultrasound showed no evidence of inflammation of pancreas. The amylase to creatinine clearance ratio, was 0.8% (reference interval 2%–5%; >6% consistent with acute pancreatitis;
ISSN:	1757-790X 1757-790X
DOI:	10.1136/bcr.02.2012.5917