Future Directions for Cardiovascular Disease Comparative Effectiveness Research: Report of a Workshop Sponsored by the National Heart, Lung, and Blood Institute
Comparative effectiveness research (CER) aims to provide decision makers with the evidence needed to evaluate the benefits and harms of alternative clinical management strategies. CER has become a national priority, with considerable new research funding allocated. Cardiovascular disease is a priori...
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Veröffentlicht in: | Journal of the American College of Cardiology 2012-08, Vol.60 (7), p.569-580 |
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creator | HLATKY, Mark A DOUGLAS, Pamela S ROGER, Véronique L SELBY, Joseph V UDELSON, James E LAUER, Michael S COOK, Nakela L WELLS, Barbara BENJAMIN, Emelia J DICKERSIN, Kay GOFF, David C HIRSCH, Alan T HYLEK, Elaine M PETERSON, Eric D |
description | Comparative effectiveness research (CER) aims to provide decision makers with the evidence needed to evaluate the benefits and harms of alternative clinical management strategies. CER has become a national priority, with considerable new research funding allocated. Cardiovascular disease is a priority area for CER. This workshop report provides an overview of CER methods, with an emphasis on practical clinical trials and observational treatment comparisons. The report also details recommendations to the National Heart, Lung, and Blood Institute for a new framework for evidence development to foster cardiovascular CER, and specific studies to address 8 clinical issues identified by the Institute of Medicine as high priorities for cardiovascular CER. |
doi_str_mv | 10.1016/j.jacc.2011.12.057 |
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Vascular system</subject><subject>Cardiovascular Diseases - therapy</subject><subject>Comparative Effectiveness Research</subject><subject>Evidence-Based Medicine</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>National Academies of Science, Engineering, and Medicine (U.S.) Health and Medicine Division</subject><subject>National Heart, Lung, and Blood Institute (U.S.)</subject><subject>Outcome Assessment (Health Care)</subject><subject>Randomized Controlled Trials as Topic</subject><subject>United States</subject><issn>0735-1097</issn><issn>1558-3597</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkc1u1DAUhS0EotPCC7BA3iCxaIIdx3bMohJMW1ppBBI_YhndSa47HjJxsJ2R-jY8Kh4x_K3ulc53zlkcQp5xVnLG1attuYWuKyvGecmrkkn9gCy4lE0hpNEPyYJpIQvOjD4hpzFuGWOq4eYxOakqbVQl9YL8uJ7THJBeuoBdcn6M1PpAlxB65_cQu3mAkNWIEJEu_W6CAMntkV5Ze3DsccQY6UfMROg2r_M3-ZCotxToVx--xY2f6KcpJ_uAPV3f07RB-h4OZTDQm2xL53Q1j3fnFMaevh287-ntGJNLc8In5JGFIeLT4z0jX66vPi9vitWHd7fLN6tiqoxKxZpz2zAB0mrNrO3ANKDRGt31lbLVuhaiFsAqVL1kBiU0tcwehQJqXQspzsjFr9xpXu-w73BMAYZ2Cm4H4b714Nr_ldFt2ju_b0XNlanrHPDyGBD89xljancudjgMMKKfY8uZEIdxlMno83-7_pT8niUDL45AXgAGG2DsXPzLqUrLWjHxE8HyoQg</recordid><startdate>20120814</startdate><enddate>20120814</enddate><creator>HLATKY, Mark A</creator><creator>DOUGLAS, Pamela S</creator><creator>ROGER, Véronique L</creator><creator>SELBY, Joseph V</creator><creator>UDELSON, James E</creator><creator>LAUER, Michael S</creator><creator>COOK, Nakela L</creator><creator>WELLS, Barbara</creator><creator>BENJAMIN, Emelia J</creator><creator>DICKERSIN, Kay</creator><creator>GOFF, David C</creator><creator>HIRSCH, Alan T</creator><creator>HYLEK, Elaine M</creator><creator>PETERSON, Eric D</creator><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20120814</creationdate><title>Future Directions for Cardiovascular Disease Comparative Effectiveness Research: Report of a Workshop Sponsored by the National Heart, Lung, and Blood Institute</title><author>HLATKY, Mark A ; DOUGLAS, Pamela S ; ROGER, Véronique L ; SELBY, Joseph V ; UDELSON, James E ; LAUER, Michael S ; COOK, Nakela L ; WELLS, Barbara ; BENJAMIN, Emelia J ; DICKERSIN, Kay ; GOFF, David C ; HIRSCH, Alan T ; HYLEK, Elaine M ; PETERSON, Eric D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p296t-b11f803a5f770ffca98a7ef97cd26f2b43343a02e6d509e5a845b116e3a474353</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Biological and medical sciences</topic><topic>Cardiology. 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subjects | Biological and medical sciences Cardiology. Vascular system Cardiovascular Diseases - therapy Comparative Effectiveness Research Evidence-Based Medicine Humans Medical sciences National Academies of Science, Engineering, and Medicine (U.S.) Health and Medicine Division National Heart, Lung, and Blood Institute (U.S.) Outcome Assessment (Health Care) Randomized Controlled Trials as Topic United States |
title | Future Directions for Cardiovascular Disease Comparative Effectiveness Research: Report of a Workshop Sponsored by the National Heart, Lung, and Blood Institute |
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