Small Sample Research Designs for Evidence-Based Rehabilitation: Issues and Methods

Abstract Graham JE, Karmarkar AM, Ottenbacher KJ. Small sample research designs for evidence-based rehabilitation: issues and methods. Conventional research methods, including randomized controlled trials, are powerful techniques for determining the efficacy of interventions. These designs, however,...

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Veröffentlicht in:Archives of physical medicine and rehabilitation 2012-08, Vol.93 (8), p.S111-S116
Hauptverfasser: Graham, James E., PhD, DC, Karmarkar, Amol M., PhD, OTR, Ottenbacher, Kenneth J., PhD, OTR
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container_end_page S116
container_issue 8
container_start_page S111
container_title Archives of physical medicine and rehabilitation
container_volume 93
creator Graham, James E., PhD, DC
Karmarkar, Amol M., PhD, OTR
Ottenbacher, Kenneth J., PhD, OTR
description Abstract Graham JE, Karmarkar AM, Ottenbacher KJ. Small sample research designs for evidence-based rehabilitation: issues and methods. Conventional research methods, including randomized controlled trials, are powerful techniques for determining the efficacy of interventions. These designs, however, have practical limitations when applied to many rehabilitation settings and research questions. Alternative methods are available that can supplement findings from traditional research designs and improve our ability to evaluate the effectiveness of treatments for individual patients. The focus on individual patients is an important element of evidenced-based rehabilitation. This article examines one such alternate approach: small-N research designs. Small-N designs usually focus on 10 or fewer participants whose behavior (outcomes) are measured repeatedly and compared over time. The advantages and limitations of various small-N designs are described and illustrated using 3 examples from the rehabilitation literature. The challenges and opportunities of applying small-N designs to enhance evidence-based rehabilitation are discussed.
doi_str_mv 10.1016/j.apmr.2011.12.017
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source MEDLINE; Access via ScienceDirect (Elsevier); EZB Electronic Journals Library
subjects Evaluation studies as topic
Evidence-Based Medicine - methods
Evidence-based practice
Humans
Physical Medicine and Rehabilitation
Rehabilitation
Rehabilitation - methods
Reproducibility of Results
Research Design
Sample Size
title Small Sample Research Designs for Evidence-Based Rehabilitation: Issues and Methods
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