Varenicline for smoking cessation: nausea severity and variation in nicotinic receptor genes

This study evaluated association between common and rare sequence variants in 10 nicotinic acetylcholine receptor subunit genes and the severity of nausea 21 days after initiating the standard, Food and Drug Administration-approved varenicline regimen for smoking cessation. A total of 397 participan...

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Veröffentlicht in:	The pharmacogenomics journal 2012-08, Vol.12 (4), p.349-358
Hauptverfasser:	Swan, G E, Javitz, H S, Jack, L M, Wessel, J, Michel, M, Hinds, D A, Stokowksi, R P, McClure, J B, Catz, S L, Richards, J, Zbikowski, S M, Deprey, M, McAfee, T, Conti, D V, Bergen, A W
Format:	Artikel
Sprache:	eng
Schlagworte:	631/378 692/700/565/1436/434 Alleles Benzazepines - adverse effects Benzazepines - therapeutic use Biomedical and Life Sciences Biomedicine Cigarette smoking Drug addiction Female Gene Expression Health aspects Human Genetics Humans Male Middle Aged Nausea Nausea - chemically induced Nausea - genetics Nicotine Nicotinic Agonists - adverse effects Oncology original-article Pharmacotherapy Physiological aspects Prevention Psychopharmacology Quinoxalines - adverse effects Quinoxalines - therapeutic use Receptors, Nicotinic - genetics Smoking and youth Smoking Cessation Varenicline
Online-Zugang:	Volltext
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