Genes of nuclear encoded mitochondrial proteins: evidence for a variant of the 3' splice-site consensus sequence

The introns of animal nuclear genes and of viral genes encoding protein possess at their 3' splice-site the consensus sequence (CT)11NTCAG (Mount, S.M. (1982) Nucl. Acids Res. 10, 459-472; Green, M.R. (1986) Ann. Rev. Genet. 20, 671-708). However, the total 39 introns of the 5 imported mitochon...

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Veröffentlicht in:Nucleic acids research 1987-12, Vol.15 (24), p.10083-10086
Hauptverfasser: JURETIC, N, JAUSSI, R, MATTES, U, CHRISTEN, P
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container_title Nucleic acids research
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creator JURETIC, N
JAUSSI, R
MATTES, U
CHRISTEN, P
description The introns of animal nuclear genes and of viral genes encoding protein possess at their 3' splice-site the consensus sequence (CT)11NTCAG (Mount, S.M. (1982) Nucl. Acids Res. 10, 459-472; Green, M.R. (1986) Ann. Rev. Genet. 20, 671-708). However, the total 39 introns of the 5 imported mitochondrial proteins of higher eucaryotes whose gene structure has been determined to date show a predominance of 44% for base T at position -4. Apparently, a variant consensus sequence, i.e. (CT)11TTCAG, characterizes the genes of nuclear encoded mitochondrial proteins.
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subjects 5-Aminolevulinate Synthetase - genetics
Aspartate Aminotransferases - genetics
Biological and medical sciences
Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing) - genetics
Cytochrome c Group - genetics
Fundamental and applied biological sciences. Psychology
Genes
Genes. Genome
Mitochondria - physiology
Molecular and cellular biology
Molecular genetics
Regulatory Sequences, Nucleic Acid
RNA Splicing
title Genes of nuclear encoded mitochondrial proteins: evidence for a variant of the 3' splice-site consensus sequence
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