Nomenclature report on the major histocompatibility complex genes and alleles of Great Ape, Old and New World monkey species

The major histocompatibility complex (MHC) plays a central role in the adaptive immune response. The MHC region is characterised by a high gene density, and most of these genes display considerable polymorphism. Next to humans, non-human primates (NHP) are well studied for their MHC. The present nom...

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Veröffentlicht in:Immunogenetics (New York) 2012-08, Vol.64 (8), p.615-631
Hauptverfasser: de Groot, Natasja G., Otting, Nel, Robinson, James, Blancher, Antoine, Lafont, Bernard A. P., Marsh, Steven G. E., O’Connor, David H., Shiina, Takashi, Walter, Lutz, Watkins, David I., Bontrop, Ronald E.
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container_issue 8
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container_title Immunogenetics (New York)
container_volume 64
creator de Groot, Natasja G.
Otting, Nel
Robinson, James
Blancher, Antoine
Lafont, Bernard A. P.
Marsh, Steven G. E.
O’Connor, David H.
Shiina, Takashi
Walter, Lutz
Watkins, David I.
Bontrop, Ronald E.
description The major histocompatibility complex (MHC) plays a central role in the adaptive immune response. The MHC region is characterised by a high gene density, and most of these genes display considerable polymorphism. Next to humans, non-human primates (NHP) are well studied for their MHC. The present nomenclature report provides the scientific community with the latest nomenclature guidelines/rules and current implemented nomenclature revisions for Great Ape, Old and New World monkey species. All the currently published MHC data for the different Great Ape, Old and New World monkey species are archived at the Immuno Polymorphism Database (IPD)-MHC NHP database. The curators of the IPD-MHC NHP database are, in addition, responsible for providing official designations for newly detected polymorphisms.
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subjects Alleles
Allergology
Animals
Biomedical and Life Sciences
Biomedicine
Cell Biology
Cercopithecidae - genetics
Databases, Genetic
Gene Function
Guidelines as Topic
Hominidae - genetics
Human Genetics
Immunology
Major Histocompatibility Complex
Original Paper
Phylogeny
Platyrrhini - genetics
Polymorphism, Genetic
Terminology as Topic
title Nomenclature report on the major histocompatibility complex genes and alleles of Great Ape, Old and New World monkey species
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