RIP-chip-SRM--a new combinatorial large-scale approach identifies a set of translationally regulated bantam/miR-58 targets in C. elegans

MicroRNAs (miRNAs) are small, noncoding RNAs that negatively regulate gene expression. As miRNAs are involved in a wide range of biological processes and diseases, much effort has been invested in identifying their mRNA targets. Here, we present a novel combinatorial approach, RIP-chip-SRM (RNA-bind...

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Veröffentlicht in:Genome research 2012-07, Vol.22 (7), p.1360-1371
Hauptverfasser: Jovanovic, Marko, Reiter, Lukas, Clark, Alejandra, Weiss, Manuel, Picotti, Paola, Rehrauer, Hubert, Frei, Andreas, Neukomm, Lukas J, Kaufman, Ethan, Wollscheid, Bernd, Simard, Martin J, Miska, Eric A, Aebersold, Ruedi, Gerber, André P, Hengartner, Michael O
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Sprache:eng
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