The Impact of Macrophage Nucleotide Pools on HIV-1 Reverse Transcription, Viral Replication, and the Development of Novel Antiviral Agents

Macrophages are ubiquitous and represent a significant viral reservoir for HIV-1. Macrophages are nondividing, terminally differentiated cells, which have a unique cellular microenvironment relative to actively dividing T lymphocytes, all of which can impact HIV-1 infection/replication, design of in...

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Veröffentlicht in:Molecular Biology International 2012-01, Vol.2012 (2012), p.219-226
Hauptverfasser: Gavegnano, Christina, Kennedy, Edward M., Kim, Baek, Schinazi, Raymond F.
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Sprache:eng
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