Evaluation of a combined treatment paradigm consisting of environmental enrichment and the 5-HT1A receptor agonist buspirone after experimental traumatic brain injury

Environmental enrichment (EE) and serotonin(1A) (5-HT(1A))-receptor agonists provide significant benefit after experimental traumatic brain injury (TBI). The aim of this study was to test the hypothesis that combining these therapies would produce an effect that is more robust than either therapy al...

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Veröffentlicht in:	Journal of neurotrauma 2012-07, Vol.29 (10), p.1960-1969
Hauptverfasser:	Kline, Anthony E, Olsen, Adam S, Sozda, Christopher N, Hoffman, Ann N, Cheng, Jeffrey P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Behavior Brain damage Brain Injuries - drug therapy Brain Injuries - physiopathology Buspirone - pharmacology Cognitive ability Combined Modality Therapy - methods Environment Head injuries Male Motor Activity - physiology Original Random Allocation Rats Rats, Sprague-Dawley Receptor, Serotonin, 5-HT1A - physiology Serotonin Serotonin Receptor Agonists - pharmacology
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