Thymidylate synthase and thymidine phosphorylase mRNA expression in primary lesions using laser capture microdissection is useful for prediction of the efficacy of FOLFOX treatment in colorectal cancer patients with liver metastasis

Chemotherapy with FOLFOX, which is a combination of 5-fluorouracil (5-FU)/leucovorin (LV) and oxaliplatin, has been used worldwide for the treatment of metastatic colorectal cancer patients. The aim of this study was to examine the candidates for predictors of the efficacy of the FOLFOX treatment re...

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Veröffentlicht in:	Oncology letters 2012-05, Vol.3 (5), p.983-989
Hauptverfasser:	KUMAMOTO, KENSUKE, KUWABARA, KOKI, TAJIMA, YUSUKE, AMANO, KUNIHIKO, HATANO, SATOSHI, OHSAWA, TOMONORI, OKADA, NORIMICHI, ISHIBASHI, KEIICHIRO, HAGA, NORIHIRO, ISHIDA, HIDEYUKI
Format:	Artikel
Sprache:	eng
Schlagworte:	colorectal cancer excision repair cross-complementing 1 FOLFOX laser capture microdissection thymidine phosphorylase thymidylate synthase
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