The Osteogenic Study of Tissue Engineering Bone with BMP2 and BMP7 Gene-Modified Rat Adipose-Derived Stem Cell

To evaluate the feasibility and advantages of constructing a novel tissue engineering bone, using β-tricalcium phosphate (β-TCP) and rat adipose-derived stem cells (ADSCs), modified with BMP2 and BMP7 by lentivirus. In the present study, ADSCs transfected with Lv-BMP2 and Lv-BMP7, alone or together,...

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Veröffentlicht in:	BioMed research international 2012-01, Vol.2012 (2012), p.1-7
Hauptverfasser:	Qing, Wang, Guang-Xing, Chen, Lin, Guo, Liu, Yang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - cytology Alkaline phosphatase Alkaline Phosphatase - metabolism Analysis of Variance Animals Anthraquinones - chemistry Biotechnology Bone marrow Bone Morphogenetic Protein 2 - genetics Bone Morphogenetic Protein 2 - metabolism Bone Morphogenetic Protein 7 - genetics Bone Morphogenetic Protein 7 - metabolism Bone Regeneration - genetics Bone Regeneration - physiology Calcium Phosphates Cell Growth Processes - physiology Femur - injuries Femur - metabolism Femur - pathology Histocytochemistry Humans Lentivirus Osteogenesis - genetics Osteogenesis - physiology Rats Rats, Sprague-Dawley Stem cells Stem Cells - cytology Stem Cells - metabolism Studies Tissue engineering Tissue Engineering - methods Tissue Scaffolds Transfection Wound Healing - genetics Wound Healing - physiology
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