Rab GTPase regulation of retromer-mediated cargo export during endosome maturation

The retromer complex, composed of sorting nexin subunits and a Vps26/Vps29/Vps35 trimer, mediates sorting of retrograde cargo from the endosome to the trans-Golgi network. The retromer trimer subcomplex is an effector of Rab7 (Ypt7 in yeast). Whereas endosome targeting of human retromer has been sho...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular biology of the cell 2012-07, Vol.23 (13), p.2505-2515
Hauptverfasser:	Liu, Ting-Ting, Gomez, Timothy S, Sackey, Bridget K, Billadeau, Daniel D, Burd, Christopher G
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Motifs Endosomes Humans Intracellular Membranes - metabolism Jurkat Cells Protein Binding Protein Interaction Domains and Motifs Protein Interaction Mapping rab GTP-Binding Proteins - chemistry rab GTP-Binding Proteins - metabolism Saccharomyces cerevisiae - enzymology Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae - physiology Saccharomyces cerevisiae Proteins - chemistry Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism Secretory Pathway Sequence Deletion Vacuoles - metabolism Vesicular Transport Proteins - chemistry Vesicular Transport Proteins - genetics Vesicular Transport Proteins - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!