8-Alkylthio-6-thio-substituted Theophylline Analogues as Selective Progesterone Receptor Antagonists

The progesterone receptor (PR) plays a key role in reproduction and is important in cancers of the reproductive tract. Current PR antagonists usually compete for progestin binding in the PR ligand-binding pocket and often exhibit cross-binding with other members of the steroid receptor family. Using...

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Veröffentlicht in:	Steroids 2012-03, Vol.77 (6), p.596-601
Hauptverfasser:	Aninye, Irene O., Berg, Kenneth C., Mollo, Andy R., Nordeen, Steven K., Wilson, Elizabeth M., Shapiro, David J.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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