Human repair gene restores normal pattern of preferential DNA repair in repair defective CHO cells

The pattern of preferential DNA repair of UV-induced pyrimidine dimers was studied in repair-deficient Chinese hamster ovary (CHO) cells transfected with the human excision repair gene, ERCC-1. Repair efficiency was measured in the active dihydrofolate reductase (DHFR) gene and in its flanking, non-...

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Veröffentlicht in:Nucleic acids research 1988-08, Vol.16 (15), p.7397-7403
Hauptverfasser: Bohr, V A, Chu, E H, van Duin, M, Hanawalt, P C, Okumoto, D S
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Sprache:eng
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