A Key Role for Lysine Residues in Amyloid β-Protein Folding, Assembly, and Toxicity

A combination of hydrophobic and electrostatic interactions is important in initiating the aberrant self-assembly process that leads to formation of toxic oligomers and aggregates by multiple disease-related proteins, including amyloid β-protein (Aβ), whose self-assembly is believed to initiate brai...

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