Application of a methylation gene panel by quantitative PCR for lung cancers

Summary Detection of lung cancer at early stages could potentially increase survival rates. One promising approach is the application of suitable lung cancer-specific biomarkers to specimens obtained by non-invasive methods. Thus far, clinically useful biomarkers that have high sensitivity have prov...

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Veröffentlicht in:	Cancer letters 2007-03, Vol.247 (1), p.56-71
Hauptverfasser:	Shivapurkar, Narayan, Stastny, Victor, Suzuki, Makoto, Wistuba, Ignacio I, Li, Lin, Zheng, Yingye, Feng, Ziding, Hol, Bernard, Prinsen, Clemens, Thunnissen, Frederik B, Gazdar, Adi F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - genetics Aged Aged, 80 and over Biomarkers Biomarkers, Tumor - analysis Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Squamous Cell - genetics Cell cycle Computer Systems Deoxyribonucleic acid DNA DNA Methylation Female Gene expression Hematology, Oncology and Palliative Medicine Humans Lung cancer Lung Neoplasms - genetics Male Medical screening Middle Aged Mortality Non-small cell lung cancer Polymerase Chain Reaction - methods Real time Real time PCR Signal transduction Sputum - metabolism Tumor suppressor gene
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