Eph/ephrin signaling in epidermal differentiation and disease

► Eph receptors and ephrin ligands are coordinately expressed in the epidermis. ► Keratinocytes communicate with one another via Eph/ephrins. ► Eph receptors regulate keratinocyte proliferation, adhesion and differentiation. ► Eph receptor and ephrin ligand expression is altered in dermatological di...

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Veröffentlicht in:	Seminars in cell & developmental biology 2012-02, Vol.23 (1), p.92-101
Hauptverfasser:	Lin, Samantha, Wang, Bingcheng, Getsios, Spiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cadherin Cell Adhesion Cell Differentiation Cell Proliferation Cell–cell communication Desmosome EphA2 Ephrins - metabolism Ephrins - physiology Epidermis - metabolism Epidermis - pathology Epithelial Humans Keratinocytes - metabolism Keratinocytes - physiology Receptors, Eph Family - metabolism Receptors, Eph Family - physiology Signal Transduction Skin Neoplasms - metabolism Skin Neoplasms - pathology Wound Healing
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