Clinical Data Mining of Phenotypic Network in Angina Pectoris of Coronary Heart Disease

Coronary heart disease (CHD) is the leading causes of morbidity and mortality in China. The diagnosis of CHD in Traditional Chinese Medicine (TCM) was mainly based on experience in the past. In this paper, we proposed four MI-based association algorithms to analyze phenotype networks of CHD, and est...

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Veröffentlicht in:Evidence-based complementary and alternative medicine 2012-01, Vol.2012 (2012), p.1-8
Hauptverfasser: Wang, Wei, Yang, Yi, Yi, Jianqiang, Luo, Liangtao, Zhao, Huihui, Shi, Qi, Zuo, Xiaohan, Lu, Peng, Chen, Jianxin, Zheng, Chenglong
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container_end_page 8
container_issue 2012
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container_title Evidence-based complementary and alternative medicine
container_volume 2012
creator Wang, Wei
Yang, Yi
Yi, Jianqiang
Luo, Liangtao
Zhao, Huihui
Shi, Qi
Zuo, Xiaohan
Lu, Peng
Chen, Jianxin
Zheng, Chenglong
description Coronary heart disease (CHD) is the leading causes of morbidity and mortality in China. The diagnosis of CHD in Traditional Chinese Medicine (TCM) was mainly based on experience in the past. In this paper, we proposed four MI-based association algorithms to analyze phenotype networks of CHD, and established scale of syndromes to automatically generate the diagnosis of patients based on their phenotypes. We also compared the change of core syndromes that CHD were combined with other diseases, and presented the different phenotype spectra.
doi_str_mv 10.1155/2012/546230
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The diagnosis of CHD in Traditional Chinese Medicine (TCM) was mainly based on experience in the past. In this paper, we proposed four MI-based association algorithms to analyze phenotype networks of CHD, and established scale of syndromes to automatically generate the diagnosis of patients based on their phenotypes. We also compared the change of core syndromes that CHD were combined with other diseases, and presented the different phenotype spectra.</description><identifier>ISSN: 1741-427X</identifier><identifier>EISSN: 1741-4288</identifier><identifier>DOI: 10.1155/2012/546230</identifier><identifier>PMID: 23002393</identifier><language>eng</language><publisher>Cairo, Egypt: Hindawi Publishing Corporation</publisher><subject>Algorithms ; Angina ; Angina pectoris ; Cardiology ; Cardiovascular disease ; Cardiovascular diseases ; Chinese medicine ; Coronary artery disease ; Data analysis ; Data mining ; Data processing ; Diagnosis ; Genotype &amp; phenotype ; Heart attacks ; Heart diseases ; Herbal medicine ; Hypertension ; Modernization ; Morbidity ; Phenotypes ; Traditional Chinese medicine</subject><ispartof>Evidence-based complementary and alternative medicine, 2012-01, Vol.2012 (2012), p.1-8</ispartof><rights>Copyright © 2012 Jianxin Chen et al.</rights><rights>Copyright © 2012 Jianxin Chen et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0</rights><rights>Copyright © 2012 Jianxin Chen et al. 2012</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c467t-7b9f5e403968f4abc6d5c42ecf427c098d877b6a5b8ee6d762613903760974e63</citedby><cites>FETCH-LOGICAL-c467t-7b9f5e403968f4abc6d5c42ecf427c098d877b6a5b8ee6d762613903760974e63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378973/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378973/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23002393$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Li, Shao</contributor><contributor>Shao Li</contributor><creatorcontrib>Wang, Wei</creatorcontrib><creatorcontrib>Yang, Yi</creatorcontrib><creatorcontrib>Yi, Jianqiang</creatorcontrib><creatorcontrib>Luo, Liangtao</creatorcontrib><creatorcontrib>Zhao, Huihui</creatorcontrib><creatorcontrib>Shi, Qi</creatorcontrib><creatorcontrib>Zuo, Xiaohan</creatorcontrib><creatorcontrib>Lu, Peng</creatorcontrib><creatorcontrib>Chen, Jianxin</creatorcontrib><creatorcontrib>Zheng, Chenglong</creatorcontrib><title>Clinical Data Mining of Phenotypic Network in Angina Pectoris of Coronary Heart Disease</title><title>Evidence-based complementary and alternative medicine</title><addtitle>Evid Based Complement Alternat Med</addtitle><description>Coronary heart disease (CHD) is the leading causes of morbidity and mortality in China. 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subjects Algorithms
Angina
Angina pectoris
Cardiology
Cardiovascular disease
Cardiovascular diseases
Chinese medicine
Coronary artery disease
Data analysis
Data mining
Data processing
Diagnosis
Genotype & phenotype
Heart attacks
Heart diseases
Herbal medicine
Hypertension
Modernization
Morbidity
Phenotypes
Traditional Chinese medicine
title Clinical Data Mining of Phenotypic Network in Angina Pectoris of Coronary Heart Disease
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