Risk factors for tuberculin skin test conversion among HIV-infected patients in New York City
Summary Background We assessed the incidence of and risk factors for tuberculin skin test (TST) conversion among HIV-infected adults at a New York City clinic. Methods All adult HIV-infected patients were eligible for inclusion if they had a negative baseline TST result and at least one subsequent d...
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| Veröffentlicht in: | International journal of infectious diseases 2012-07, Vol.16 (7), p.e518-e521 |
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| container_title | International journal of infectious diseases |
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| creator | Doshi, Saumil Chen, Tina Fang Zapata, Josue Holzman, Robert S Zapata, Luis C Aberg, Judith A Sivapalasingam, Sumathi |
| description | Summary Background We assessed the incidence of and risk factors for tuberculin skin test (TST) conversion among HIV-infected adults at a New York City clinic. Methods All adult HIV-infected patients were eligible for inclusion if they had a negative baseline TST result and at least one subsequent documented TST test result. Results A total of 414 HIV-infected patients had a negative baseline TST result; 288 (69.6%) were male. Among 348 patients who had a place of birth documented, 50% were born outside of mainland USA. Twenty-two (5.3%) of 414 patients had documented TST conversions, giving a crude incidence rate of 1.77 per 100 person-years. Being a foreign-born Asian individual ( p = 0.02), having lived in a shelter ( p = 0.004), and having an increase in CD4 cell count ( p = 0.02) while under care were independent risk factors for TST conversion. Conclusions We found a high TST conversion rate among HIV-infected patients attending an urban clinic. Annual TST testing is particularly important for patients who are foreign-born from high-endemic countries, those with a history of homelessness, and those with an increase in CD4 cell count since the baseline negative TST test. |
| doi_str_mv | 10.1016/j.ijid.2012.03.002 |
| format | Article |
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Methods All adult HIV-infected patients were eligible for inclusion if they had a negative baseline TST result and at least one subsequent documented TST test result. Results A total of 414 HIV-infected patients had a negative baseline TST result; 288 (69.6%) were male. Among 348 patients who had a place of birth documented, 50% were born outside of mainland USA. Twenty-two (5.3%) of 414 patients had documented TST conversions, giving a crude incidence rate of 1.77 per 100 person-years. Being a foreign-born Asian individual ( p = 0.02), having lived in a shelter ( p = 0.004), and having an increase in CD4 cell count ( p = 0.02) while under care were independent risk factors for TST conversion. Conclusions We found a high TST conversion rate among HIV-infected patients attending an urban clinic. Annual TST testing is particularly important for patients who are foreign-born from high-endemic countries, those with a history of homelessness, and those with an increase in CD4 cell count since the baseline negative TST test.</description><identifier>ISSN: 1201-9712</identifier><identifier>EISSN: 1878-3511</identifier><identifier>DOI: 10.1016/j.ijid.2012.03.002</identifier><identifier>PMID: 22542005</identifier><language>eng</language><publisher>Canada: Elsevier Ltd</publisher><subject>Adult ; Aged ; AIDS-Related Opportunistic Infections - complications ; AIDS-Related Opportunistic Infections - diagnosis ; AIDS-Related Opportunistic Infections - epidemiology ; CD4 Lymphocyte Count ; Diagnosis ; Female ; HIV ; HIV Infections - complications ; HIV Infections - epidemiology ; Humans ; Incidence ; Infectious Disease ; Latent tuberculosis infection ; Male ; Middle Aged ; New York City - epidemiology ; Pulmonary/Respiratory ; Risk Factors ; Tuberculin skin test ; Tuberculin Test ; Tuberculosis - complications ; Tuberculosis - diagnosis ; Tuberculosis - epidemiology ; Young Adult</subject><ispartof>International journal of infectious diseases, 2012-07, Vol.16 (7), p.e518-e521</ispartof><rights>International Society for Infectious Diseases</rights><rights>2012 International Society for Infectious Diseases</rights><rights>Copyright © 2012 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.</rights><rights>2012 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved 2012</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c510t-ea2ee29dc5e4a695bc3920285c91f2a548444e95984d7d5cf64ec7d60ba79b263</citedby><cites>FETCH-LOGICAL-c510t-ea2ee29dc5e4a695bc3920285c91f2a548444e95984d7d5cf64ec7d60ba79b263</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S120197121200094X$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>230,314,776,780,860,881,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22542005$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Doshi, Saumil</creatorcontrib><creatorcontrib>Chen, Tina Fang</creatorcontrib><creatorcontrib>Zapata, Josue</creatorcontrib><creatorcontrib>Holzman, Robert S</creatorcontrib><creatorcontrib>Zapata, Luis C</creatorcontrib><creatorcontrib>Aberg, Judith A</creatorcontrib><creatorcontrib>Sivapalasingam, Sumathi</creatorcontrib><title>Risk factors for tuberculin skin test conversion among HIV-infected patients in New York City</title><title>International journal of infectious diseases</title><addtitle>Int J Infect Dis</addtitle><description>Summary Background We assessed the incidence of and risk factors for tuberculin skin test (TST) conversion among HIV-infected adults at a New York City clinic. Methods All adult HIV-infected patients were eligible for inclusion if they had a negative baseline TST result and at least one subsequent documented TST test result. Results A total of 414 HIV-infected patients had a negative baseline TST result; 288 (69.6%) were male. Among 348 patients who had a place of birth documented, 50% were born outside of mainland USA. Twenty-two (5.3%) of 414 patients had documented TST conversions, giving a crude incidence rate of 1.77 per 100 person-years. Being a foreign-born Asian individual ( p = 0.02), having lived in a shelter ( p = 0.004), and having an increase in CD4 cell count ( p = 0.02) while under care were independent risk factors for TST conversion. Conclusions We found a high TST conversion rate among HIV-infected patients attending an urban clinic. Annual TST testing is particularly important for patients who are foreign-born from high-endemic countries, those with a history of homelessness, and those with an increase in CD4 cell count since the baseline negative TST test.</description><subject>Adult</subject><subject>Aged</subject><subject>AIDS-Related Opportunistic Infections - complications</subject><subject>AIDS-Related Opportunistic Infections - diagnosis</subject><subject>AIDS-Related Opportunistic Infections - epidemiology</subject><subject>CD4 Lymphocyte Count</subject><subject>Diagnosis</subject><subject>Female</subject><subject>HIV</subject><subject>HIV Infections - complications</subject><subject>HIV Infections - epidemiology</subject><subject>Humans</subject><subject>Incidence</subject><subject>Infectious Disease</subject><subject>Latent tuberculosis infection</subject><subject>Male</subject><subject>Middle Aged</subject><subject>New York City - epidemiology</subject><subject>Pulmonary/Respiratory</subject><subject>Risk Factors</subject><subject>Tuberculin skin test</subject><subject>Tuberculin Test</subject><subject>Tuberculosis - complications</subject><subject>Tuberculosis - diagnosis</subject><subject>Tuberculosis - epidemiology</subject><subject>Young Adult</subject><issn>1201-9712</issn><issn>1878-3511</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9Uk1v1DAQjRCIlsIf4IB85JIwduwkllAltAJaqQKJL8EBWY4zKd7Nxls7WbT_nom2VMCBi8fSvPc8fm-y7CmHggOvXqwLv_ZdIYCLAsoCQNzLTnlTN3mpOL9Pd2rluubiJHuU0hoAZFU1D7MTIZQUAOo0-_7Bpw3rrZtCTKwPkU1zi9HNgx9Z2tAxYZqYC-MeY_JhZHYbxmt2cfkl92OPbsKO7ezkcZwSI_g7_Mm-hbhhKz8dHmcPejskfHJbz7LPb15_Wl3kV-_fXq5eXeVOcZhytAJR6M4plLbSqnWlFiAa5TTvhVWykVKiVrqRXd0p11cSXd1V0Npat6Iqz7Lzo-5ubrfYORom2sHsot_aeDDBevN3Z_Q_zHXYm7KsyS9NAs9vBWK4menHZuuTw2GwI4Y5GQ6CC1WLmhNUHKEuhpQi9nfPcDBLLmZtllzMkouB0lAuRHr254B3lN9BEODlEYBk095jNMmRpw47H8lk0wX_f_3zf-iOAvTODhs8YFqHOY4UgOEmEcd8XDZjWQyqAFp-LX8BmGC1Cw</recordid><startdate>20120701</startdate><enddate>20120701</enddate><creator>Doshi, Saumil</creator><creator>Chen, Tina Fang</creator><creator>Zapata, Josue</creator><creator>Holzman, Robert S</creator><creator>Zapata, Luis C</creator><creator>Aberg, Judith A</creator><creator>Sivapalasingam, Sumathi</creator><general>Elsevier Ltd</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20120701</creationdate><title>Risk factors for tuberculin skin test conversion among HIV-infected patients in New York City</title><author>Doshi, Saumil ; Chen, Tina Fang ; Zapata, Josue ; Holzman, Robert S ; Zapata, Luis C ; Aberg, Judith A ; Sivapalasingam, Sumathi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c510t-ea2ee29dc5e4a695bc3920285c91f2a548444e95984d7d5cf64ec7d60ba79b263</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adult</topic><topic>Aged</topic><topic>AIDS-Related Opportunistic Infections - complications</topic><topic>AIDS-Related Opportunistic Infections - diagnosis</topic><topic>AIDS-Related Opportunistic Infections - epidemiology</topic><topic>CD4 Lymphocyte Count</topic><topic>Diagnosis</topic><topic>Female</topic><topic>HIV</topic><topic>HIV Infections - complications</topic><topic>HIV Infections - epidemiology</topic><topic>Humans</topic><topic>Incidence</topic><topic>Infectious Disease</topic><topic>Latent tuberculosis infection</topic><topic>Male</topic><topic>Middle Aged</topic><topic>New York City - epidemiology</topic><topic>Pulmonary/Respiratory</topic><topic>Risk Factors</topic><topic>Tuberculin skin test</topic><topic>Tuberculin Test</topic><topic>Tuberculosis - complications</topic><topic>Tuberculosis - diagnosis</topic><topic>Tuberculosis - epidemiology</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Doshi, Saumil</creatorcontrib><creatorcontrib>Chen, Tina Fang</creatorcontrib><creatorcontrib>Zapata, Josue</creatorcontrib><creatorcontrib>Holzman, Robert S</creatorcontrib><creatorcontrib>Zapata, Luis C</creatorcontrib><creatorcontrib>Aberg, Judith A</creatorcontrib><creatorcontrib>Sivapalasingam, Sumathi</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>International journal of infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Doshi, Saumil</au><au>Chen, Tina Fang</au><au>Zapata, Josue</au><au>Holzman, Robert S</au><au>Zapata, Luis C</au><au>Aberg, Judith A</au><au>Sivapalasingam, Sumathi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Risk factors for tuberculin skin test conversion among HIV-infected patients in New York City</atitle><jtitle>International journal of infectious diseases</jtitle><addtitle>Int J Infect Dis</addtitle><date>2012-07-01</date><risdate>2012</risdate><volume>16</volume><issue>7</issue><spage>e518</spage><epage>e521</epage><pages>e518-e521</pages><issn>1201-9712</issn><eissn>1878-3511</eissn><abstract>Summary Background We assessed the incidence of and risk factors for tuberculin skin test (TST) conversion among HIV-infected adults at a New York City clinic. Methods All adult HIV-infected patients were eligible for inclusion if they had a negative baseline TST result and at least one subsequent documented TST test result. Results A total of 414 HIV-infected patients had a negative baseline TST result; 288 (69.6%) were male. Among 348 patients who had a place of birth documented, 50% were born outside of mainland USA. Twenty-two (5.3%) of 414 patients had documented TST conversions, giving a crude incidence rate of 1.77 per 100 person-years. Being a foreign-born Asian individual ( p = 0.02), having lived in a shelter ( p = 0.004), and having an increase in CD4 cell count ( p = 0.02) while under care were independent risk factors for TST conversion. Conclusions We found a high TST conversion rate among HIV-infected patients attending an urban clinic. Annual TST testing is particularly important for patients who are foreign-born from high-endemic countries, those with a history of homelessness, and those with an increase in CD4 cell count since the baseline negative TST test.</abstract><cop>Canada</cop><pub>Elsevier Ltd</pub><pmid>22542005</pmid><doi>10.1016/j.ijid.2012.03.002</doi><oa>free_for_read</oa></addata></record> |
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| subjects | Adult Aged AIDS-Related Opportunistic Infections - complications AIDS-Related Opportunistic Infections - diagnosis AIDS-Related Opportunistic Infections - epidemiology CD4 Lymphocyte Count Diagnosis Female HIV HIV Infections - complications HIV Infections - epidemiology Humans Incidence Infectious Disease Latent tuberculosis infection Male Middle Aged New York City - epidemiology Pulmonary/Respiratory Risk Factors Tuberculin skin test Tuberculin Test Tuberculosis - complications Tuberculosis - diagnosis Tuberculosis - epidemiology Young Adult |
| title | Risk factors for tuberculin skin test conversion among HIV-infected patients in New York City |
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