Testing in a Prespecified Subgroup and the Intent-to-Treat Population

In many settings, testing has been proposed to assess the effect of an experimental regimen within a biomarker-positive subgroup where it is biologically plausible that benefit is stronger in such patients, and in the overall population that also includes biomarker-negative subjects less likely to b...

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Bibliographische Detailangaben

Veröffentlicht in:	Drug information journal 2012-03, Vol.46 (2), p.175-179
Hauptverfasser:	Rothmann, Mark D., Zhang, Jenny J., Lu, Laura, Fleming, Thomas R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Clinical Trials Drug Safety and Pharmacovigilance Pharmacotherapy Pharmacy
Online-Zugang:	Volltext
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