Nanochannel-Based Single Molecule Recycling

We present a method for measuring the fluorescence from a single molecule hundreds of times without surface immobilization. The approach is based on the use of electroosmosis to repeatedly drive a single target molecule in a fused silica nanochannel through a stationary laser focus. Single molecule...

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Veröffentlicht in:	Nano letters 2012-06, Vol.12 (6), p.3273-3278
Hauptverfasser:	Lesoine, John F, Venkataraman, Prahnesh A, Maloney, Peter C, Dumont, Mark E, Novotny, Lukas
Format:	Artikel
Sprache:	eng
Schlagworte:	Condensed matter: structure, mechanical and thermal properties Diffusion coefficient Diffusion in nanoscale solids Diffusion in solids Dynamic tests Electric potential Energy transfer Exact sciences and technology Fluorescence Lasers Molecular Imaging - methods Nanoparticles - analysis Nanoparticles - chemistry Nanoparticles - ultrastructure Nanostructure Physics Recycling Spectrometry, Fluorescence - methods Transit time Transport properties of condensed matter (nonelectronic)
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