Oxidative Stress : A Pathogenic Mechanism for Niemann-Pick Type C Disease

Niemann-Pick type C (NPC) disease is a neurovisceral atypical lipid storage disorder involving the accumulation of cholesterol and other lipids in the late endocytic pathway. The pathogenic mechanism that links the accumulation of intracellular cholesterol with cell death in NPC disease in both the...

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Veröffentlicht in:	Oxidative medicine and cellular longevity 2012-01, Vol.2012 (2012), p.1-11
Hauptverfasser:	Zanlungo, Silvana, Alvarez, Alejandra R., Balboa, Elisa, Vázquez, Mary Carmen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain - metabolism Cholesterol - metabolism Glycosphingolipids - metabolism Liver - metabolism Mitochondria - metabolism Niemann-Pick Disease, Type C - metabolism Niemann-Pick Disease, Type C - pathology Oxidative Stress Peroxisomes - metabolism Proteins - metabolism Review Vitamin E - metabolism
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