FUS Immunogold Labeling TEM Analysis of the Neuronal Cytoplasmic Inclusions of Neuronal Intermediate Filament Inclusion Disease: A Frontotemporal Lobar Degeneration with FUS Proteinopathy

Fused in sarcoma (FUS)-immunoreactive neuronal and glial inclusions define a novel molecular pathology called FUS proteinopathy. FUS has been shown to be a component of inclusions of familial amyotrophic lateral sclerosis with FUS mutation and three frontotemporal lobar degeneration entities, includ...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of molecular neuroscience 2011-11, Vol.45 (3), p.409-421
Hauptverfasser:	Page, Tristan, Gitcho, Michael A., Mosaheb, Sabrina, Carter, Deborah, Chakraverty, Sumi, Perry, Robert H., Bigio, Eileen H., Gearing, Marla, Ferrer, Isidre, Goate, Alison M., Cairns, Nigel J., Thorpe, Julian R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Alzheimer's disease Amyotrophic lateral sclerosis Biomedical and Life Sciences Biomedicine Brain - pathology Cell Biology Cytomegalic inclusion disease Cytoplasm Dementia Esclerosi lateral amiotròfica Euchromatin Female Frontotemporal dementia Frontotemporal Lobar Degeneration - metabolism Frontotemporal Lobar Degeneration - pathology FUS gene FUS protein Genotype & phenotype Humans Immunoelectron microscopy Immunohistochemistry Immunoreactivity Inclusion bodies Inclusion Bodies - pathology Intermediate filaments Intermediate Filaments - metabolism Intermediate Filaments - pathology Malalties neurodegeneratives Male Medicine Microscopy Microscopy, Electron, Transmission - methods Microscopy, Immunoelectron - methods Middle Aged Motor neurone disease Mutation Nervous system Neurochemistry Neurodegenerative diseases Neurofilament protein Neurofilament Proteins - metabolism Neurology Neuronal-glial interactions Neurons - pathology Neurosciences Pathology Proteins Proteomics RNA RNA-Binding Protein FUS - metabolism Sarcoma
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!