Biofunctionalized Magnetic Nanoparticles for Specifically Detecting Biomarkers of Alzheimer’s Disease in Vitro

Magnetic nanoparticles biofunctionalized with antibodies against β-amyloid-40 (Aβ-40) and Aβ-42, which are promising biomarkers related to Alzheimer’s disease (AD), were synthesized. We characterized the size distribution, saturated magnetizations, and stability of the magnetic nanoparticles conjuga...

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Veröffentlicht in:	ACS chemical neuroscience 2011-09, Vol.2 (9), p.500-505
Hauptverfasser:	Yang, Che-Chuan, Yang, Shieh-Yueh, Chieh, Jen-Jie, Horng, Herng-Er, Hong, Chin-Yih, Yang, Hong-Chang, Chen, K. H, Shih, B. Y, Chen, Ta-Fu, Chiu, Ming-Jang
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Alzheimer Disease - metabolism Amyloid beta-Peptides - analysis Amyloid beta-Peptides - chemistry Amyloid beta-Peptides - immunology Antibodies - chemistry Antibodies - immunology Biomarkers Enzyme-Linked Immunosorbent Assay Humans Immunochemistry Indicators and Reagents Magnetic Resonance Imaging Magnetics Nanoparticles Particle Size Peptide Fragments - analysis Peptide Fragments - chemistry Peptide Fragments - immunology
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