Detection of Toxin Translocation into the Host Cytosol by Surface Plasmon Resonance

AB toxins consist of an enzymatic A subunit and a cell-binding B subunit1. These toxins are secreted into the extracellular milieu, but they act upon targets within the eukaryotic cytosol. Some AB toxins travel by vesicle carriers from the cell surface to the endoplasmic reticulum (ER) before enteri...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of Visualized Experiments 2012-01 (59), p.e3686
Hauptverfasser:	Taylor, Michael, Banerjee, Tuhina, VanBennekom, Neyda, Teter, Ken
Format:	Artikel
Sprache:	eng
Schlagworte:	Cholera Toxin - analysis Cholera Toxin - metabolism Cytosol - chemistry Cytosol - metabolism Endoplasmic Reticulum - metabolism HeLa Cells Humans Immunology Surface Plasmon Resonance - methods Toxins, Biological - analysis Toxins, Biological - metabolism
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!