Expression of epidermal growth factor variant III (EGFRvIII) in pediatric diffuse intrinsic pontine gliomas

Despite numerous clinical trials over the past 2 decades, the overall survival for children diagnosed with diffuse intrinsic pontine glioma (DIPG) remains 9–10 months. Radiation therapy is the only treatment with proven effect and novel therapies are needed. Epidermal growth factor receptor variant...

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Veröffentlicht in:	Journal of neuro-oncology 2012-07, Vol.108 (3), p.395-402
Hauptverfasser:	Li, Gordon, Mitra, Siddhartha S., Monje, Michelle, Henrich, Kristy N., Bangs, C. Dana, Nitta, Ryan T., Wong, Albert J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antibodies Blotting, Western Brain Stem Neoplasms - genetics Brain Stem Neoplasms - metabolism Brain tumors Cell culture Child, Preschool Children Clinical trials Data processing Epidermal growth factor Epidermal growth factor receptors Flow Cytometry Glioblastoma Glioma Humans Immunoenzyme Techniques Immunohistochemistry In Situ Hybridization, Fluorescence Laboratory Investigation Medicine Medicine & Public Health Neurology Oncology Pediatrics Peptide Fragments - immunology Polymerase chain reaction Prognosis Receptor, Epidermal Growth Factor - genetics Receptor, Epidermal Growth Factor - metabolism Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics Survival Tumors Vaccines Western blotting
Online-Zugang:	Volltext
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