Comprehensive analysis of unique cases with extraordinary control over HIV replication

True long-term nonprogressors (LTNPs)/elite controllers (ECs) maintain durable control over HIV replication without antiretroviral therapy. Herein we describe 4 unique persons who were distinct from conventional LTNPs/ECs in that they had extraordinarily low HIV burdens and comparatively weak immune...

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Veröffentlicht in:	Blood 2012-05, Vol.119 (20), p.4645-4655
Hauptverfasser:	Mendoza, Daniel, Johnson, Sarah A., Peterson, Bennett A., Natarajan, Ven, Salgado, Maria, Dewar, Robin L., Burbelo, Peter D., Doria-Rose, Nicole A., Graf, Erin H., Greenwald, Jamieson H., Hodge, Jessica N., Thompson, William L., Cogliano, Nancy A., Chairez, Cheryl L., Rehm, Catherine A., Jones, Sara, Hallahan, Claire W., Kovacs, Joseph A., Sereti, Irini, Sued, Omar, Peel, Sheila A., O'Connell, Robert J., O'Doherty, Una, Chun, Tae-Wook, Connors, Mark, Migueles, Stephen A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Female Hematologic and hematopoietic diseases HIV Infections - blood HIV Infections - immunology HIV Infections - virology HIV Long-Term Survivors HIV Seropositivity - immunology HIV Seropositivity - virology HIV-1 - immunology HIV-1 - physiology Human viral diseases Humans Immunobiology Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infectious diseases Male Medical sciences Middle Aged Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Viral Load Virus Replication - immunology Virus Replication - physiology
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