Regulation and function of autophagy during cell survival and cell death

Autophagy is an important catabolic process that delivers cytoplasmic material to the lysosome for degradation. Autophagy promotes cell survival by elimination of damaged organelles and proteins aggregates, as well as by facilitating bioenergetic homeostasis. Although autophagy has been considered a...

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Veröffentlicht in:Cold Spring Harbor perspectives in biology 2012-06, Vol.4 (6), p.a008813-a008813
Hauptverfasser: Das, Gautam, Shravage, Bhupendra V, Baehrecke, Eric H
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Sprache:eng
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