Claudin 6： a novel surface marker for characterizing mouse pluripotent stem cells
Dear Editor, Stem cell surface proteins have been used as markers for isolating and purifying undifferentiated pluripotent stem cells （PSCs）, and play important roles in regulat- ing their pluripotency and differentiation. To date, very few specific, highly sensitive markers in PSCs have been identi...
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| Veröffentlicht in: | Cell research 2012-06, Vol.22 (6), p.1082-1085 |
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| container_title | Cell research |
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| creator | Wang, Linlin Xue, Yan Shen, Yihang Li, Wei Cheng, Yan Yan, Xiaoshuang Shi, Wansheng Wang, Juan Gong, Zhijuan Yang, Guanheng Guo, Chuanliang Zhou, Yiye Wang, Xiang Zhou, Qi Zeng, Fanyi |
| description | Dear Editor,
Stem cell surface proteins have been used as markers for isolating and purifying undifferentiated pluripotent stem cells （PSCs）, and play important roles in regulat- ing their pluripotency and differentiation. To date, very few specific, highly sensitive markers in PSCs have been identified [1-3]. This severely limits their utility in the analysis and recovery of functionally important PSCs. Therefore, it is necessary to expand the repertoire of stem cell markers and to dissect out the molecular mechanisms that regulate pluripotency and differentiation. |
| doi_str_mv | 10.1038/cr.2012.77 |
| format | Article |
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Stem cell surface proteins have been used as markers for isolating and purifying undifferentiated pluripotent stem cells （PSCs）, and play important roles in regulat- ing their pluripotency and differentiation. To date, very few specific, highly sensitive markers in PSCs have been identified [1-3]. This severely limits their utility in the analysis and recovery of functionally important PSCs. Therefore, it is necessary to expand the repertoire of stem cell markers and to dissect out the molecular mechanisms that regulate pluripotency and differentiation.</description><identifier>ISSN: 1001-0602</identifier><identifier>EISSN: 1748-7838</identifier><identifier>DOI: 10.1038/cr.2012.77</identifier><identifier>PMID: 22565286</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>631/532/2064 ; 631/80 ; 692/53 ; Animals ; Biomedical and Life Sciences ; Cell Biology ; Cell Differentiation ; Claudins - genetics ; Claudins - metabolism ; Down-Regulation ; Embryonic Stem Cells - cytology ; Embryonic Stem Cells - metabolism ; Gene Expression Profiling ; Homeodomain Proteins - metabolism ; Letter to the Editor ; Life Sciences ; Mice ; Nanog Homeobox Protein ; Octamer Transcription Factor-3 - metabolism ; Pluripotent Stem Cells - cytology ; Pluripotent Stem Cells - metabolism ; PSCS ; SOXB1 Transcription Factors - metabolism ; Stem cells ; 多能干细胞 ; 小鼠 ; 恢复功能 ; 特征 ; 紧密连接 ; 细胞标记 ; 细胞表面</subject><ispartof>Cell research, 2012-06, Vol.22 (6), p.1082-1085</ispartof><rights>Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2012</rights><rights>Copyright Nature Publishing Group Jun 2012</rights><rights>Copyright © 2012 Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2012 Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c468t-e644c61626d9c391be0e97f5e5cefbc88e792e19f169878770e559130eb99df3</citedby><cites>FETCH-LOGICAL-c468t-e644c61626d9c391be0e97f5e5cefbc88e792e19f169878770e559130eb99df3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/85240X/85240X.jpg</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367520/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367520/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,315,728,781,785,886,27928,27929,53795,53797</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22565286$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wang, Linlin</creatorcontrib><creatorcontrib>Xue, Yan</creatorcontrib><creatorcontrib>Shen, Yihang</creatorcontrib><creatorcontrib>Li, Wei</creatorcontrib><creatorcontrib>Cheng, Yan</creatorcontrib><creatorcontrib>Yan, Xiaoshuang</creatorcontrib><creatorcontrib>Shi, Wansheng</creatorcontrib><creatorcontrib>Wang, Juan</creatorcontrib><creatorcontrib>Gong, Zhijuan</creatorcontrib><creatorcontrib>Yang, Guanheng</creatorcontrib><creatorcontrib>Guo, Chuanliang</creatorcontrib><creatorcontrib>Zhou, Yiye</creatorcontrib><creatorcontrib>Wang, Xiang</creatorcontrib><creatorcontrib>Zhou, Qi</creatorcontrib><creatorcontrib>Zeng, Fanyi</creatorcontrib><title>Claudin 6： a novel surface marker for characterizing mouse pluripotent stem cells</title><title>Cell research</title><addtitle>Cell Res</addtitle><addtitle>Cell Research</addtitle><description>Dear Editor,
Stem cell surface proteins have been used as markers for isolating and purifying undifferentiated pluripotent stem cells （PSCs）, and play important roles in regulat- ing their pluripotency and differentiation. To date, very few specific, highly sensitive markers in PSCs have been identified [1-3]. This severely limits their utility in the analysis and recovery of functionally important PSCs. Therefore, it is necessary to expand the repertoire of stem cell markers and to dissect out the molecular mechanisms that regulate pluripotency and differentiation.</description><subject>631/532/2064</subject><subject>631/80</subject><subject>692/53</subject><subject>Animals</subject><subject>Biomedical and Life Sciences</subject><subject>Cell Biology</subject><subject>Cell Differentiation</subject><subject>Claudins - genetics</subject><subject>Claudins - metabolism</subject><subject>Down-Regulation</subject><subject>Embryonic Stem Cells - cytology</subject><subject>Embryonic Stem Cells - metabolism</subject><subject>Gene Expression Profiling</subject><subject>Homeodomain Proteins - metabolism</subject><subject>Letter to the Editor</subject><subject>Life Sciences</subject><subject>Mice</subject><subject>Nanog Homeobox Protein</subject><subject>Octamer Transcription Factor-3 - metabolism</subject><subject>Pluripotent Stem Cells - cytology</subject><subject>Pluripotent Stem Cells - metabolism</subject><subject>PSCS</subject><subject>SOXB1 Transcription Factors - metabolism</subject><subject>Stem cells</subject><subject>多能干细胞</subject><subject>小鼠</subject><subject>恢复功能</subject><subject>特征</subject><subject>紧密连接</subject><subject>细胞标记</subject><subject>细胞表面</subject><issn>1001-0602</issn><issn>1748-7838</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNptkU1OHDEQhS2UCAiwyQEiR9kgoh780_7bREKjkERCygL2lsdTPdOk2x7sbiQ4CmfhTrlCPJnJiERZ2VJ99eq9KoTeUjKhhOtznyaMUDZRag8dUlXrSmmuX5U_IbQikrAD9CbnW0KYqAXdRweMCSmYlofoetq5cd4GLH8-P2GHQ7yHDucxNc4D7l36AQk3MWG_dMn5AVL72IYF7uOYAa-6MbWrOEAYcB6gxx66Lh-j143rMpxs3yN0c_n5Zvq1uvr-5dv04qrytdRDBbKuvaSSybnx3NAZEDCqESA8NDOvNSjDgJqGSqOVVoqAEIZyAjNj5g0_Qp82sqtx1sPcFxPJdXaV2mL7wUbX2r8roV3aRby3nEslGCkCp1uBFO9GyIPt27xO4AKUeJYSqrUsu2IF_fAPehvHFEq63xRXZbF1oc42lE8x5wTNzgwldn0q65Ndn8oqVeB3L-3v0D-3KcDHDZBLKSwgvZz5H7n329nLGBZ3pWGnWDPGmaoZ_wVNCKnn</recordid><startdate>20120601</startdate><enddate>20120601</enddate><creator>Wang, Linlin</creator><creator>Xue, Yan</creator><creator>Shen, Yihang</creator><creator>Li, Wei</creator><creator>Cheng, Yan</creator><creator>Yan, Xiaoshuang</creator><creator>Shi, Wansheng</creator><creator>Wang, Juan</creator><creator>Gong, Zhijuan</creator><creator>Yang, Guanheng</creator><creator>Guo, Chuanliang</creator><creator>Zhou, Yiye</creator><creator>Wang, Xiang</creator><creator>Zhou, Qi</creator><creator>Zeng, Fanyi</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W94</scope><scope>WU4</scope><scope>~WA</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7QP</scope><scope>7QR</scope><scope>7T5</scope><scope>7TK</scope><scope>7TM</scope><scope>7TO</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20120601</creationdate><title>Claudin 6： a novel surface marker for characterizing mouse pluripotent stem cells</title><author>Wang, Linlin ; Xue, Yan ; Shen, Yihang ; Li, Wei ; Cheng, Yan ; Yan, Xiaoshuang ; Shi, Wansheng ; Wang, Juan ; Gong, Zhijuan ; Yang, Guanheng ; Guo, Chuanliang ; Zhou, Yiye ; Wang, Xiang ; Zhou, Qi ; Zeng, Fanyi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c468t-e644c61626d9c391be0e97f5e5cefbc88e792e19f169878770e559130eb99df3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>631/532/2064</topic><topic>631/80</topic><topic>692/53</topic><topic>Animals</topic><topic>Biomedical and Life Sciences</topic><topic>Cell Biology</topic><topic>Cell Differentiation</topic><topic>Claudins - genetics</topic><topic>Claudins - metabolism</topic><topic>Down-Regulation</topic><topic>Embryonic Stem Cells - cytology</topic><topic>Embryonic Stem Cells - metabolism</topic><topic>Gene Expression Profiling</topic><topic>Homeodomain Proteins - metabolism</topic><topic>Letter to the Editor</topic><topic>Life Sciences</topic><topic>Mice</topic><topic>Nanog Homeobox Protein</topic><topic>Octamer Transcription Factor-3 - metabolism</topic><topic>Pluripotent Stem Cells - cytology</topic><topic>Pluripotent Stem Cells - metabolism</topic><topic>PSCS</topic><topic>SOXB1 Transcription Factors - metabolism</topic><topic>Stem cells</topic><topic>多能干细胞</topic><topic>小鼠</topic><topic>恢复功能</topic><topic>特征</topic><topic>紧密连接</topic><topic>细胞标记</topic><topic>细胞表面</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wang, Linlin</creatorcontrib><creatorcontrib>Xue, Yan</creatorcontrib><creatorcontrib>Shen, Yihang</creatorcontrib><creatorcontrib>Li, Wei</creatorcontrib><creatorcontrib>Cheng, Yan</creatorcontrib><creatorcontrib>Yan, Xiaoshuang</creatorcontrib><creatorcontrib>Shi, Wansheng</creatorcontrib><creatorcontrib>Wang, Juan</creatorcontrib><creatorcontrib>Gong, Zhijuan</creatorcontrib><creatorcontrib>Yang, Guanheng</creatorcontrib><creatorcontrib>Guo, Chuanliang</creatorcontrib><creatorcontrib>Zhou, Yiye</creatorcontrib><creatorcontrib>Wang, Xiang</creatorcontrib><creatorcontrib>Zhou, Qi</creatorcontrib><creatorcontrib>Zeng, Fanyi</creatorcontrib><collection>中文科技期刊数据库</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>中文科技期刊数据库-7.0平台</collection><collection>中文科技期刊数据库-自然科学</collection><collection>中文科技期刊数据库-自然科学-生物科学</collection><collection>中文科技期刊数据库- 镜像站点</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Cell research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wang, Linlin</au><au>Xue, Yan</au><au>Shen, Yihang</au><au>Li, Wei</au><au>Cheng, Yan</au><au>Yan, Xiaoshuang</au><au>Shi, Wansheng</au><au>Wang, Juan</au><au>Gong, Zhijuan</au><au>Yang, Guanheng</au><au>Guo, Chuanliang</au><au>Zhou, Yiye</au><au>Wang, Xiang</au><au>Zhou, Qi</au><au>Zeng, Fanyi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Claudin 6： a novel surface marker for characterizing mouse pluripotent stem cells</atitle><jtitle>Cell research</jtitle><stitle>Cell Res</stitle><addtitle>Cell Research</addtitle><date>2012-06-01</date><risdate>2012</risdate><volume>22</volume><issue>6</issue><spage>1082</spage><epage>1085</epage><pages>1082-1085</pages><issn>1001-0602</issn><eissn>1748-7838</eissn><abstract>Dear Editor,
Stem cell surface proteins have been used as markers for isolating and purifying undifferentiated pluripotent stem cells （PSCs）, and play important roles in regulat- ing their pluripotency and differentiation. To date, very few specific, highly sensitive markers in PSCs have been identified [1-3]. This severely limits their utility in the analysis and recovery of functionally important PSCs. Therefore, it is necessary to expand the repertoire of stem cell markers and to dissect out the molecular mechanisms that regulate pluripotency and differentiation.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>22565286</pmid><doi>10.1038/cr.2012.77</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection |
| subjects | 631/532/2064 631/80 692/53 Animals Biomedical and Life Sciences Cell Biology Cell Differentiation Claudins - genetics Claudins - metabolism Down-Regulation Embryonic Stem Cells - cytology Embryonic Stem Cells - metabolism Gene Expression Profiling Homeodomain Proteins - metabolism Letter to the Editor Life Sciences Mice Nanog Homeobox Protein Octamer Transcription Factor-3 - metabolism Pluripotent Stem Cells - cytology Pluripotent Stem Cells - metabolism PSCS SOXB1 Transcription Factors - metabolism Stem cells 多能干细胞 小鼠 恢复功能 特征 紧密连接 细胞标记 细胞表面 |
| title | Claudin 6： a novel surface marker for characterizing mouse pluripotent stem cells |
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