Tbr2 is essential for hippocampal lineage progression from neural stem cells to intermediate progenitors and neurons

Neurogenesis in the dentate gyrus has been implicated in cognitive functions, including learning and memory, and may be abnormal in major neuropsychiatric disorders, such as depression. Dentate neurogenesis is regulated by interactions between extrinsic factors and intrinsic transcriptional cascades...

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Veröffentlicht in:	The Journal of neuroscience 2012-05, Vol.32 (18), p.6275-6287
Hauptverfasser:	Hodge, Rebecca D, Nelson, Branden R, Kahoud, Robert J, Yang, Roderick, Mussar, Kristin E, Reiner, Steven L, Hevner, Robert F
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - metabolism Aging - pathology Animals Cell Differentiation - physiology Hippocampus - cytology Hippocampus - metabolism Mice Mice, Inbred C57BL Mice, Transgenic Neural Stem Cells - cytology Neural Stem Cells - metabolism Neurogenesis - physiology Neurons - cytology Neurons - metabolism T-Box Domain Proteins - metabolism
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