Vesicular and conductive mechanisms of nucleotide release

Extracellular nucleotides and nucleosides promote a vast range of physiological responses, via activation of cell surface purinergic receptors. Virtually all tissues and cell types exhibit regulated release of ATP, which, in many cases, is accompanied by the release of uridine nucleotides. Given the...

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Veröffentlicht in:	Purinergic signalling 2012-09, Vol.8 (3), p.359-373
1. Verfasser:	Lazarowski, Eduardo R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Adenosine Triphosphate - physiology Animals Anion channels ATP Biomedical and Life Sciences Biomedicine Cancer Research Cell activation Cell surface Connexins Connexins - metabolism Connexins - physiology Cytoplasmic Vesicles - metabolism Cytoplasmic Vesicles - physiology Exocytosis Human Physiology Humans Neurosciences nucleosides Nucleotides Nucleotides - metabolism Nucleotides - physiology Pharmacology/Toxicology Plasma membranes Purine receptors Receptors, Purinergic - physiology Review Secretory vesicles Signal transduction Signal Transduction - physiology TRPV Cation Channels - physiology Uridine Uridine Diphosphate - metabolism Uridine Diphosphate - physiology
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