A Proof-of-Concept Randomized Controlled Study of Gabapentin: Effects on Cannabis Use, Withdrawal and Executive Function Deficits in Cannabis-Dependent Adults

There are no FDA-approved pharmacotherapies for cannabis dependence. Cannabis is the most widely used illicit drug in the world, and patients seeking treatment for primary cannabis dependence represent 25% of all substance use admissions. We conducted a phase IIa proof-of-concept pilot study to exam...

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Veröffentlicht in:	Neuropsychopharmacology (New York, N.Y.) N.Y.), 2012-06, Vol.37 (7), p.1689-1698
Hauptverfasser:	J MASON, Barbara, CREAN, Rebecca, GOODELL, Vivian, M LIGHT, John, QUELLO FARHAD SHADAN, Susan, BUFFKINS, Kimberly, KYLE, Mark, ADUSUMALLI, Murali, BEGOVIC, Adnan, RAO, Santosh
Format:	Artikel
Sprache:	eng
Schlagworte:	Abstinence Addictions Addictive behaviors Adolescent Adult Adult and adolescent clinical studies Amines - pharmacology Amines - therapeutic use Biological and medical sciences Brain research Calcium Channel Blockers - pharmacology Calcium Channel Blockers - therapeutic use Cannabis - adverse effects Clinical trials Counseling Cyclohexanecarboxylic Acids - pharmacology Cyclohexanecarboxylic Acids - therapeutic use Desintoxication. Drug withdrawal Double-Blind Method Drug addiction Drug therapy Drug use Drug withdrawal Executive function Executive Function - drug effects FDA approval Female gamma-Aminobutyric Acid - pharmacology gamma-Aminobutyric Acid - therapeutic use Humans Male Marijuana Marijuana Abuse - drug therapy Marijuana Abuse - psychology Marijuana Abuse - therapy Medical sciences Middle Aged Neurosciences Original Pilot projects Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Research centers Substance Withdrawal Syndrome - drug therapy Substance Withdrawal Syndrome - psychology Substance Withdrawal Syndrome - therapy Tetrahydrocannabinol THC Toxicology Treatment Outcome Treatments
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