Anticancer Activity of Certain Herbs and Spices on the Cervical Epithelial Carcinoma (HeLa) Cell Line
Acetone extracts of selected plant species were evaluated for their in vitro cytotoxicity against a noncancerous African green monkey kidney (Vero) cell line and an adenocarcinoma cervical cancer (HeLa) cell line. The plants studied were Origanum vulgare L. (Oregano), Rosmarinus officinalis L. (Upri...
Gespeichert in:
Veröffentlicht in: | Evidence-based complementary and alternative medicine 2012-01, Vol.2012 (2012), p.1-11 |
---|---|
Hauptverfasser: | , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 11 |
---|---|
container_issue | 2012 |
container_start_page | 1 |
container_title | Evidence-based complementary and alternative medicine |
container_volume | 2012 |
creator | Berrington, Danielle Lall, Namrita |
description | Acetone extracts of selected plant species were evaluated for their in vitro cytotoxicity against a noncancerous African green monkey kidney (Vero) cell line and an adenocarcinoma cervical cancer (HeLa) cell line. The plants studied were Origanum vulgare L. (Oregano), Rosmarinus officinalis L. (Upright and ground cove rosemary), Lavandula spica L. (Lavender), Laurus nobilis L. (Bay leaf), Thymus vulgaris L. (Thyme), Lavandula x intermedia L. (Margaret Roberts Lavender), Petroselinum crispum Mill. (Curly leaved parsley), Foeniculum vulgare Mill. (Fennel), and Capsicum annuum L. (Paprika). Antioxidant activity was determined using a quantitative DPPH (1,1-diphenyl-2-picryl hydrazyl) assay. The rosemary species exhibited effective radical scavenging capacity with 50% inhibitory concentration (IC50) of 3.48±0.218 μg/mL and 10.84±0.125 μg/mL and vitamin C equivalents of 0.351 g and 1.09 g for McConnell’s Blue and Tuscan Blue, respectively. Cytotoxicity was measured using XTT (Sodium 3′-[1-(phenyl amino-carbonyl)-3,4-tetrazolium]-bis-[4-methoxy-6-nitro] benzene sulfonic acid hydrate) colorimetric assay. Only L. nobilis and O. vulgare exhibited pronounced effects on the HeLa cell line. Dose-dependent studies revealed IC50 of 34.46±0.48 μg/mL and 126.3±1.00 μg/mL on the HeLa cells and on the Vero cells 124.1 μg/mL ± 18.26 and 163.8 μg/mL ± 2.95 for L. nobilis and O. vulgare, respectively. Light (eosin and haematoxylin staining) and confocal microscopy (Hoechst 33342, acridine orange, and propidium iodide staining) were used to evaluate the cytotoxic mechanism of action for L. nobilis and O. vulgare. |
doi_str_mv | 10.1155/2012/564927 |
format | Article |
fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3357546</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1018368780</sourcerecordid><originalsourceid>FETCH-LOGICAL-c466t-157c7b36406b9d967d6cca49a70c56d9474918dd3ce8063191198ce6fc73a0eb3</originalsourceid><addsrcrecordid>eNqFkc1rVDEUxYNYbK2uXCsBN9UyNl8vHxthGKpTGHChgruQl3efk_ImmSZvRvrfm-HVQbuRu8gN93cP53IQekXJB0qb5ooRyq4aKQxTT9AZVYLOBNP66bFXP07R81JuCWFGKfUMnTJWcaHEGYJ5HIN30UPGcz-GfRjvcerxAvLoQsRLyG3BLnb46zZ4KDhFPK7hMN_XvQFfb0P9D6G2C5d9iGnj8MUSVu5dhYYBr0KEF-ikd0OBlw_vOfr-6frbYjlbffl8s5ivZl5IOc5oo7xquRREtqYzUnXSeyeMU8Q3sjs4NlR3HfegieTUUGq0B9l7xR2Blp-jj5PudtduoPMQx-wGu81h4_K9TS7YfycxrO3PtLecN6oRsgpcPAjkdLeDMtpNKL6e4SKkXbGUUM2lVppU9O0j9DbtcqznWUYk0bUIq9TlRPmcSsnQH81QYg_x2UN8doqv0m_-9n9k_-RVgfcTsA6xc7_Cf9ReTzBUBHp3hI1hglL-G9MDqnU</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2060808002</pqid></control><display><type>article</type><title>Anticancer Activity of Certain Herbs and Spices on the Cervical Epithelial Carcinoma (HeLa) Cell Line</title><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central Open Access</source><source>Wiley-Blackwell Open Access Titles</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Berrington, Danielle ; Lall, Namrita</creator><contributor>Kuete, Victor ; Victor Kuete</contributor><creatorcontrib>Berrington, Danielle ; Lall, Namrita ; Kuete, Victor ; Victor Kuete</creatorcontrib><description>Acetone extracts of selected plant species were evaluated for their in vitro cytotoxicity against a noncancerous African green monkey kidney (Vero) cell line and an adenocarcinoma cervical cancer (HeLa) cell line. The plants studied were Origanum vulgare L. (Oregano), Rosmarinus officinalis L. (Upright and ground cove rosemary), Lavandula spica L. (Lavender), Laurus nobilis L. (Bay leaf), Thymus vulgaris L. (Thyme), Lavandula x intermedia L. (Margaret Roberts Lavender), Petroselinum crispum Mill. (Curly leaved parsley), Foeniculum vulgare Mill. (Fennel), and Capsicum annuum L. (Paprika). Antioxidant activity was determined using a quantitative DPPH (1,1-diphenyl-2-picryl hydrazyl) assay. The rosemary species exhibited effective radical scavenging capacity with 50% inhibitory concentration (IC50) of 3.48±0.218 μg/mL and 10.84±0.125 μg/mL and vitamin C equivalents of 0.351 g and 1.09 g for McConnell’s Blue and Tuscan Blue, respectively. Cytotoxicity was measured using XTT (Sodium 3′-[1-(phenyl amino-carbonyl)-3,4-tetrazolium]-bis-[4-methoxy-6-nitro] benzene sulfonic acid hydrate) colorimetric assay. Only L. nobilis and O. vulgare exhibited pronounced effects on the HeLa cell line. Dose-dependent studies revealed IC50 of 34.46±0.48 μg/mL and 126.3±1.00 μg/mL on the HeLa cells and on the Vero cells 124.1 μg/mL ± 18.26 and 163.8 μg/mL ± 2.95 for L. nobilis and O. vulgare, respectively. Light (eosin and haematoxylin staining) and confocal microscopy (Hoechst 33342, acridine orange, and propidium iodide staining) were used to evaluate the cytotoxic mechanism of action for L. nobilis and O. vulgare.</description><identifier>ISSN: 1741-427X</identifier><identifier>EISSN: 1741-4288</identifier><identifier>DOI: 10.1155/2012/564927</identifier><identifier>PMID: 22649474</identifier><language>eng</language><publisher>Cairo, Egypt: Hindawi Publishing Corporation</publisher><subject>Acetone ; Acridine orange ; Adenocarcinoma ; Antibiotics ; Antioxidants ; Antitumor activity ; Apoptosis ; Ascorbic acid ; Benzene ; Benzenesulfonic acids ; Biochemistry ; Cancer therapies ; Capsicum annuum ; Cell cycle ; Cell growth ; Cervical cancer ; Cervix ; Colorimetry ; Confocal microscopy ; Cytotoxicity ; Flavonoids ; Foeniculum vulgare ; Gangrene ; Iodides ; Laurus nobilis ; Lavandula intermedia ; Lavandula spica ; Microscopy ; Nutrition research ; Oregano ; Origanum vulgare ; Peppers ; Petroselinum crispum ; Plant extracts ; Propidium iodide ; Rosemary ; Rosmarinus officinalis ; Sodium ; Spices ; Staining ; Sulfonic acid ; Thyme ; Thymus vulgaris ; Vero cells ; Vitamin C</subject><ispartof>Evidence-based complementary and alternative medicine, 2012-01, Vol.2012 (2012), p.1-11</ispartof><rights>Copyright © 2012 Danielle Berrington and Namrita Lall.</rights><rights>Copyright © 2012 Danielle Berrington and Namrita Lall. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0</rights><rights>Copyright © 2012 D. Berrington and N. Lall. 2012</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c466t-157c7b36406b9d967d6cca49a70c56d9474918dd3ce8063191198ce6fc73a0eb3</citedby><cites>FETCH-LOGICAL-c466t-157c7b36406b9d967d6cca49a70c56d9474918dd3ce8063191198ce6fc73a0eb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357546/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357546/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,886,27926,27927,53793,53795</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22649474$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Kuete, Victor</contributor><contributor>Victor Kuete</contributor><creatorcontrib>Berrington, Danielle</creatorcontrib><creatorcontrib>Lall, Namrita</creatorcontrib><title>Anticancer Activity of Certain Herbs and Spices on the Cervical Epithelial Carcinoma (HeLa) Cell Line</title><title>Evidence-based complementary and alternative medicine</title><addtitle>Evid Based Complement Alternat Med</addtitle><description>Acetone extracts of selected plant species were evaluated for their in vitro cytotoxicity against a noncancerous African green monkey kidney (Vero) cell line and an adenocarcinoma cervical cancer (HeLa) cell line. The plants studied were Origanum vulgare L. (Oregano), Rosmarinus officinalis L. (Upright and ground cove rosemary), Lavandula spica L. (Lavender), Laurus nobilis L. (Bay leaf), Thymus vulgaris L. (Thyme), Lavandula x intermedia L. (Margaret Roberts Lavender), Petroselinum crispum Mill. (Curly leaved parsley), Foeniculum vulgare Mill. (Fennel), and Capsicum annuum L. (Paprika). Antioxidant activity was determined using a quantitative DPPH (1,1-diphenyl-2-picryl hydrazyl) assay. The rosemary species exhibited effective radical scavenging capacity with 50% inhibitory concentration (IC50) of 3.48±0.218 μg/mL and 10.84±0.125 μg/mL and vitamin C equivalents of 0.351 g and 1.09 g for McConnell’s Blue and Tuscan Blue, respectively. Cytotoxicity was measured using XTT (Sodium 3′-[1-(phenyl amino-carbonyl)-3,4-tetrazolium]-bis-[4-methoxy-6-nitro] benzene sulfonic acid hydrate) colorimetric assay. Only L. nobilis and O. vulgare exhibited pronounced effects on the HeLa cell line. Dose-dependent studies revealed IC50 of 34.46±0.48 μg/mL and 126.3±1.00 μg/mL on the HeLa cells and on the Vero cells 124.1 μg/mL ± 18.26 and 163.8 μg/mL ± 2.95 for L. nobilis and O. vulgare, respectively. Light (eosin and haematoxylin staining) and confocal microscopy (Hoechst 33342, acridine orange, and propidium iodide staining) were used to evaluate the cytotoxic mechanism of action for L. nobilis and O. vulgare.</description><subject>Acetone</subject><subject>Acridine orange</subject><subject>Adenocarcinoma</subject><subject>Antibiotics</subject><subject>Antioxidants</subject><subject>Antitumor activity</subject><subject>Apoptosis</subject><subject>Ascorbic acid</subject><subject>Benzene</subject><subject>Benzenesulfonic acids</subject><subject>Biochemistry</subject><subject>Cancer therapies</subject><subject>Capsicum annuum</subject><subject>Cell cycle</subject><subject>Cell growth</subject><subject>Cervical cancer</subject><subject>Cervix</subject><subject>Colorimetry</subject><subject>Confocal microscopy</subject><subject>Cytotoxicity</subject><subject>Flavonoids</subject><subject>Foeniculum vulgare</subject><subject>Gangrene</subject><subject>Iodides</subject><subject>Laurus nobilis</subject><subject>Lavandula intermedia</subject><subject>Lavandula spica</subject><subject>Microscopy</subject><subject>Nutrition research</subject><subject>Oregano</subject><subject>Origanum vulgare</subject><subject>Peppers</subject><subject>Petroselinum crispum</subject><subject>Plant extracts</subject><subject>Propidium iodide</subject><subject>Rosemary</subject><subject>Rosmarinus officinalis</subject><subject>Sodium</subject><subject>Spices</subject><subject>Staining</subject><subject>Sulfonic acid</subject><subject>Thyme</subject><subject>Thymus vulgaris</subject><subject>Vero cells</subject><subject>Vitamin C</subject><issn>1741-427X</issn><issn>1741-4288</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>RHX</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkc1rVDEUxYNYbK2uXCsBN9UyNl8vHxthGKpTGHChgruQl3efk_ImmSZvRvrfm-HVQbuRu8gN93cP53IQekXJB0qb5ooRyq4aKQxTT9AZVYLOBNP66bFXP07R81JuCWFGKfUMnTJWcaHEGYJ5HIN30UPGcz-GfRjvcerxAvLoQsRLyG3BLnb46zZ4KDhFPK7hMN_XvQFfb0P9D6G2C5d9iGnj8MUSVu5dhYYBr0KEF-ikd0OBlw_vOfr-6frbYjlbffl8s5ivZl5IOc5oo7xquRREtqYzUnXSeyeMU8Q3sjs4NlR3HfegieTUUGq0B9l7xR2Blp-jj5PudtduoPMQx-wGu81h4_K9TS7YfycxrO3PtLecN6oRsgpcPAjkdLeDMtpNKL6e4SKkXbGUUM2lVppU9O0j9DbtcqznWUYk0bUIq9TlRPmcSsnQH81QYg_x2UN8doqv0m_-9n9k_-RVgfcTsA6xc7_Cf9ReTzBUBHp3hI1hglL-G9MDqnU</recordid><startdate>20120101</startdate><enddate>20120101</enddate><creator>Berrington, Danielle</creator><creator>Lall, Namrita</creator><general>Hindawi Publishing Corporation</general><general>Hindawi Limited</general><scope>ADJCN</scope><scope>AHFXO</scope><scope>RHU</scope><scope>RHW</scope><scope>RHX</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7T5</scope><scope>7TO</scope><scope>7X7</scope><scope>7XB</scope><scope>88G</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M2M</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20120101</creationdate><title>Anticancer Activity of Certain Herbs and Spices on the Cervical Epithelial Carcinoma (HeLa) Cell Line</title><author>Berrington, Danielle ; Lall, Namrita</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c466t-157c7b36406b9d967d6cca49a70c56d9474918dd3ce8063191198ce6fc73a0eb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Acetone</topic><topic>Acridine orange</topic><topic>Adenocarcinoma</topic><topic>Antibiotics</topic><topic>Antioxidants</topic><topic>Antitumor activity</topic><topic>Apoptosis</topic><topic>Ascorbic acid</topic><topic>Benzene</topic><topic>Benzenesulfonic acids</topic><topic>Biochemistry</topic><topic>Cancer therapies</topic><topic>Capsicum annuum</topic><topic>Cell cycle</topic><topic>Cell growth</topic><topic>Cervical cancer</topic><topic>Cervix</topic><topic>Colorimetry</topic><topic>Confocal microscopy</topic><topic>Cytotoxicity</topic><topic>Flavonoids</topic><topic>Foeniculum vulgare</topic><topic>Gangrene</topic><topic>Iodides</topic><topic>Laurus nobilis</topic><topic>Lavandula intermedia</topic><topic>Lavandula spica</topic><topic>Microscopy</topic><topic>Nutrition research</topic><topic>Oregano</topic><topic>Origanum vulgare</topic><topic>Peppers</topic><topic>Petroselinum crispum</topic><topic>Plant extracts</topic><topic>Propidium iodide</topic><topic>Rosemary</topic><topic>Rosmarinus officinalis</topic><topic>Sodium</topic><topic>Spices</topic><topic>Staining</topic><topic>Sulfonic acid</topic><topic>Thyme</topic><topic>Thymus vulgaris</topic><topic>Vero cells</topic><topic>Vitamin C</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Berrington, Danielle</creatorcontrib><creatorcontrib>Lall, Namrita</creatorcontrib><collection>الدوريات العلمية والإحصائية - e-Marefa Academic and Statistical Periodicals</collection><collection>معرفة - المحتوى العربي الأكاديمي المتكامل - e-Marefa Academic Complete</collection><collection>Hindawi Publishing Complete</collection><collection>Hindawi Publishing Subscription Journals</collection><collection>Hindawi Publishing Open Access</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Immunology Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Psychology Database (Alumni)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Evidence-based complementary and alternative medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Berrington, Danielle</au><au>Lall, Namrita</au><au>Kuete, Victor</au><au>Victor Kuete</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Anticancer Activity of Certain Herbs and Spices on the Cervical Epithelial Carcinoma (HeLa) Cell Line</atitle><jtitle>Evidence-based complementary and alternative medicine</jtitle><addtitle>Evid Based Complement Alternat Med</addtitle><date>2012-01-01</date><risdate>2012</risdate><volume>2012</volume><issue>2012</issue><spage>1</spage><epage>11</epage><pages>1-11</pages><issn>1741-427X</issn><eissn>1741-4288</eissn><abstract>Acetone extracts of selected plant species were evaluated for their in vitro cytotoxicity against a noncancerous African green monkey kidney (Vero) cell line and an adenocarcinoma cervical cancer (HeLa) cell line. The plants studied were Origanum vulgare L. (Oregano), Rosmarinus officinalis L. (Upright and ground cove rosemary), Lavandula spica L. (Lavender), Laurus nobilis L. (Bay leaf), Thymus vulgaris L. (Thyme), Lavandula x intermedia L. (Margaret Roberts Lavender), Petroselinum crispum Mill. (Curly leaved parsley), Foeniculum vulgare Mill. (Fennel), and Capsicum annuum L. (Paprika). Antioxidant activity was determined using a quantitative DPPH (1,1-diphenyl-2-picryl hydrazyl) assay. The rosemary species exhibited effective radical scavenging capacity with 50% inhibitory concentration (IC50) of 3.48±0.218 μg/mL and 10.84±0.125 μg/mL and vitamin C equivalents of 0.351 g and 1.09 g for McConnell’s Blue and Tuscan Blue, respectively. Cytotoxicity was measured using XTT (Sodium 3′-[1-(phenyl amino-carbonyl)-3,4-tetrazolium]-bis-[4-methoxy-6-nitro] benzene sulfonic acid hydrate) colorimetric assay. Only L. nobilis and O. vulgare exhibited pronounced effects on the HeLa cell line. Dose-dependent studies revealed IC50 of 34.46±0.48 μg/mL and 126.3±1.00 μg/mL on the HeLa cells and on the Vero cells 124.1 μg/mL ± 18.26 and 163.8 μg/mL ± 2.95 for L. nobilis and O. vulgare, respectively. Light (eosin and haematoxylin staining) and confocal microscopy (Hoechst 33342, acridine orange, and propidium iodide staining) were used to evaluate the cytotoxic mechanism of action for L. nobilis and O. vulgare.</abstract><cop>Cairo, Egypt</cop><pub>Hindawi Publishing Corporation</pub><pmid>22649474</pmid><doi>10.1155/2012/564927</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1741-427X |
ispartof | Evidence-based complementary and alternative medicine, 2012-01, Vol.2012 (2012), p.1-11 |
issn | 1741-427X 1741-4288 |
language | eng |
recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3357546 |
source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; Wiley-Blackwell Open Access Titles; PubMed Central; Alma/SFX Local Collection |
subjects | Acetone Acridine orange Adenocarcinoma Antibiotics Antioxidants Antitumor activity Apoptosis Ascorbic acid Benzene Benzenesulfonic acids Biochemistry Cancer therapies Capsicum annuum Cell cycle Cell growth Cervical cancer Cervix Colorimetry Confocal microscopy Cytotoxicity Flavonoids Foeniculum vulgare Gangrene Iodides Laurus nobilis Lavandula intermedia Lavandula spica Microscopy Nutrition research Oregano Origanum vulgare Peppers Petroselinum crispum Plant extracts Propidium iodide Rosemary Rosmarinus officinalis Sodium Spices Staining Sulfonic acid Thyme Thymus vulgaris Vero cells Vitamin C |
title | Anticancer Activity of Certain Herbs and Spices on the Cervical Epithelial Carcinoma (HeLa) Cell Line |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-18T05%3A01%3A23IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Anticancer%20Activity%20of%20Certain%20Herbs%20and%20Spices%20on%20the%20Cervical%20Epithelial%20Carcinoma%20(HeLa)%20Cell%20Line&rft.jtitle=Evidence-based%20complementary%20and%20alternative%20medicine&rft.au=Berrington,%20Danielle&rft.date=2012-01-01&rft.volume=2012&rft.issue=2012&rft.spage=1&rft.epage=11&rft.pages=1-11&rft.issn=1741-427X&rft.eissn=1741-4288&rft_id=info:doi/10.1155/2012/564927&rft_dat=%3Cproquest_pubme%3E1018368780%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2060808002&rft_id=info:pmid/22649474&rfr_iscdi=true |