Beneficial effects of fucoidan in patients with chronic hepatitis C virus infection

AIM：To evaluate the effects of fucoidan,a complex sulfated polysaccharide extract from marine seaweed,on hepatitis C virus（HCV） RNA load both in vitro and in vivo.METHODS：HCV-1b replicon-expressing cells were cultured in the presence of fucoidan obtained from Cladosiphon okamuranus Tokida cultivated...

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Veröffentlicht in:	World journal of gastroenterology : WJG 2012-05, Vol.18 (18), p.2225-2230
Hauptverfasser:	Mori, Naoki, Nakasone, Kazunori, Tomimori, Koh, Ishikawa, Chie
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Alanine Transaminase - blood Antiviral Agents - adverse effects Antiviral Agents - therapeutic use Brief Carcinoma, Hepatocellular - drug therapy Carcinoma, Hepatocellular - virology Cell Line, Tumor Dose-Response Relationship, Drug Female Hepacivirus - drug effects Hepacivirus - genetics Hepatitis C, Chronic - complications Hepatitis C, Chronic - diagnosis Hepatitis C, Chronic - drug therapy Humans Japan Liver Cirrhosis - drug therapy Liver Cirrhosis - virology Liver Neoplasms - drug therapy Liver Neoplasms - virology Male Middle Aged Pilot Projects Polysaccharides - adverse effects Polysaccharides - therapeutic use RNA, Viral - blood Time Factors Treatment Outcome Viral Load 丙型肝炎病毒临床症状患者慢性有益作用海藻硫酸多糖病毒感染褐藻多糖硫酸酯
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