Detection and Analysis of Proteins Modified by O‐Linked N‐Acetylglucosamine

O‐GlcNAc is a common post‐translational modification of nuclear, mitochondrial, and cytoplasmic proteins that is implicated in the etiology of type II diabetes and Alzheimer's disease, as well as cardioprotection. This unit covers simple and comprehensive techniques for identifying proteins mod...

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Veröffentlicht in:	Current Protocols in Protein Science 2011-11, Vol.66 (1), p.12.8.1-12.8.33
Hauptverfasser:	Zachara, Natasha E., Vosseller, Keith, Hart, Gerald W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylglucosamine - metabolism analysis Antibodies - metabolism Cell Nucleus - metabolism Chromatography, Affinity detection galactosyltransferase Galactosyltransferases - metabolism Glycosylation Hexosaminidases - metabolism method(s) Mitochondria - metabolism O‐GlcNAc O‐linked Protein Processing, Post-Translational Proteins - analysis Proteins - isolation & purification Proteins - metabolism signal transduction
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