In vivo responses of cutaneous C-mechanosensitive neurons in mouse to punctate chemical stimuli that elicit itch and nociceptive sensations in humans

Native cowhage spicules, and heat-inactivated spicules containing histamine or capsaicin, evoke similar sensations of itch and nociceptive sensations in humans. In ongoing studies of the peripheral neural mechanisms of chemical itch and pain in the mouse, extracellular electrophysiological recording...

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Veröffentlicht in:	Journal of neurophysiology 2012-01, Vol.107 (1), p.357-363
Hauptverfasser:	Ma, C, Nie, H, Gu, Q, Sikand, P, Lamotte, R H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Histamine - toxicity Male Mechanoreceptors - drug effects Mechanotransduction, Cellular - drug effects Mice Mice, Inbred C57BL Mucuna - chemistry Mucuna - toxicity Mucuna pruriens Nociceptive Pain - etiology Nociceptive Pain - physiopathology Physical Stimulation - methods Pruritus - etiology Pruritus - physiopathology Skin - innervation Skin - pathology Skin - physiopathology Stimulation, Chemical
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