Nucleotide sequence of infectious bursal disease virus genome segment A delineates two major open reading frames

The genome of infectious bursal disease virus (IBDV) consists of two segments of double stranded RNA. The authors have determined the sequence of the larger segment A, encoding 3 structural polypeptides, of IBDV strain Cu-1. Sequencing of overlapping cDNA clones revealed the presence of two major op...

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Veröffentlicht in:Nucleic acids research 1989-10, Vol.17 (19), p.7982-7982
Hauptverfasser: SPIES, U, MÜLLER, H, BECHT, H
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MÜLLER, H
BECHT, H
description The genome of infectious bursal disease virus (IBDV) consists of two segments of double stranded RNA. The authors have determined the sequence of the larger segment A, encoding 3 structural polypeptides, of IBDV strain Cu-1. Sequencing of overlapping cDNA clones revealed the presence of two major open reading frames (ORFs). In addition to a large ORF (nucleotides 96 to 3132), they found a small ORF (nucleotides 62 to 497), overlapping the large ORF. Another start codon, at position 30, lies between a perfect Kozak consensus sequence; this ORF is terminated at position 60, prior to the start codons of the major ORFs.
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Genome</topic><topic>genomes</topic><topic>Infectious bursal disease virus</topic><topic>Infectious bursal disease virus - genetics</topic><topic>Molecular and cellular biology</topic><topic>Molecular genetics</topic><topic>Molecular Sequence Data</topic><topic>Reoviridae - genetics</topic><topic>Viral Structural Proteins - genetics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SPIES, U</creatorcontrib><creatorcontrib>MÜLLER, H</creatorcontrib><creatorcontrib>BECHT, H</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Biochemistry Abstracts 3</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Nucleic acids research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SPIES, U</au><au>MÜLLER, H</au><au>BECHT, H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Nucleotide sequence of infectious bursal disease virus genome segment A delineates two major open reading frames</atitle><jtitle>Nucleic acids research</jtitle><addtitle>Nucleic Acids Res</addtitle><date>1989-10-11</date><risdate>1989</risdate><volume>17</volume><issue>19</issue><spage>7982</spage><epage>7982</epage><pages>7982-7982</pages><issn>0305-1048</issn><eissn>1362-4962</eissn><coden>NARHAD</coden><abstract>The genome of infectious bursal disease virus (IBDV) consists of two segments of double stranded RNA. 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source Oxford University Press Journals Digital Archive legacy; MEDLINE; PubMed Central
subjects Base Sequence
Biological and medical sciences
Fundamental and applied biological sciences. Psychology
genes
Genes, Viral
Genes. Genome
genomes
Infectious bursal disease virus
Infectious bursal disease virus - genetics
Molecular and cellular biology
Molecular genetics
Molecular Sequence Data
Reoviridae - genetics
Viral Structural Proteins - genetics
title Nucleotide sequence of infectious bursal disease virus genome segment A delineates two major open reading frames
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