Matrix eQTL: ultra fast eQTL analysis via large matrix operations

Expression quantitative trait loci (eQTL) analysis links variations in gene expression levels to genotypes. For modern datasets, eQTL analysis is a computationally intensive task as it involves testing for association of billions of transcript-SNP (single-nucleotide polymorphism) pair. The heavy com...

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Veröffentlicht in:	Bioinformatics (Oxford, England) England), 2012-05, Vol.28 (10), p.1353-1358
1. Verfasser:	SHABALIN, Andrey A
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Biological and medical sciences Cystic Fibrosis - genetics Fundamental and applied biological sciences. Psychology Gene Expression General aspects Genotype Humans Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects) Models, Genetic Original Papers Polymorphism, Single Nucleotide Quantitative Trait Loci Software
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