Outcome Measures of Chinese Herbal Medicine for Coronary Heart Disease: An Overview of Systematic Reviews
The aim of this overview was to summarize the outcome measures of Chinese herbal medicine (CHM) as the treatment of coronary heart disease (CHD) based on available systematic reviews (SRs), so as to display the current situation and evaluate the potential benefits and advantages of CHM on CHD. Metho...
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| description | The aim of this overview was to summarize the outcome measures of Chinese herbal medicine (CHM) as the treatment of coronary heart disease (CHD) based on available systematic reviews (SRs), so as to display the current situation and evaluate the potential benefits and advantages of CHM on CHD. Methods. An extensive search included the Cochrane Database of Systematic Reviews, MEDLINE, and 4 databases in Chinese. SRs of CHM for CHD were included. Besides evaluating and summarizing the outcome measures, we also estimated the quality of the included reviews by PRISMA (preferred reporting items for systematic reviews and meta-analyses). Data were extracted according to predefined inclusion criteria by two independent reviewers. Results. 46 articles were included. 20 kinds of CHM were reviewed. 7 SRs were concerned with myocardial infarction (MI), 38 SRs were related to angina pectoris. 11 SRs had primary endpoints, while others focused on secondary endpoints to evaluate CHM for CHD such as angina pectoris and electrocardiogram (ECG). One SR reported more adverse effects of CHM for CHD and of the SRs analyzed quality of life. Many CHM appeared to have significant effect on improving symptoms, ECG, biomarkers and so on. However, most SRs failed to make a definite conclusion for the effectiveness of CHM in CHD patients due specifically to the poor evidence. And according to PRISMA we found most of the trials in the SRs were of low quality. Conclusion. Primary endpoints were not used widely. The benefits of CHM for CHD need to be confirmed in the future with RCTs of more persuasive primary endpoints and high-quality SRs. |
| doi_str_mv | 10.1155/2012/927392 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3347864</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2060808131</sourcerecordid><originalsourceid>FETCH-LOGICAL-c466t-8379fcf979589b40fd3f23bc30fc46f7d8b9734230f331fb010318fc22fff7153</originalsourceid><addsrcrecordid>eNqFkdtLHDEYxYNYqt32yWcl4Etp2ZrLzCTxoSDbyxYsC72AbyGT-aKRmYkmMyv-9812dKm-9CnJd345OeEgdEDJB0rL8oQRyk4UE1yxHbRPRUHnBZNyd7sXF3voVUrXhDAlhHiJ9hirSMWI2Ed-NQ42dIC_g0ljhISDw4sr30MCvIRYmzZLjbd5gl2IeBFi6E28z6KJA_7kU74Ip_isx6s1xLWHu43Fz_s0QGcGb_EP2AzTa_TCmTbBm4d1hn5_-fxrsZyfr75-W5ydz21RVcNccqGcdUqoUqq6IK7hjvHacuIy4EQjayV4wfKZc-pqQgmn0lnGnHOClnyGPk6-N2PdQWOhH6Jp9U30XY6tg_H6qdL7K30Z1przQsiqyAZvHwxiuB0hDbrzyULbmh7CmDQltCSqLP-ix8_Q6zDGPn9PM1IRSSTlNFPvJ8rGkFIEtw1Did5UqDcV6qnCTB_9m3_LPnaWgXcTkFtqzJ3_j9vhBOcy8stmC6sMCMX_AKEbrPc</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2060808131</pqid></control><display><type>article</type><title>Outcome Measures of Chinese Herbal Medicine for Coronary Heart Disease: An Overview of Systematic Reviews</title><source>Wiley-Blackwell Open Access Titles</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><source>PubMed Central Open Access</source><creator>Luo, Jing ; Xu, Hao</creator><contributor>Chen, Keji ; Keji Chen</contributor><creatorcontrib>Luo, Jing ; Xu, Hao ; Chen, Keji ; Keji Chen</creatorcontrib><description>The aim of this overview was to summarize the outcome measures of Chinese herbal medicine (CHM) as the treatment of coronary heart disease (CHD) based on available systematic reviews (SRs), so as to display the current situation and evaluate the potential benefits and advantages of CHM on CHD. Methods. An extensive search included the Cochrane Database of Systematic Reviews, MEDLINE, and 4 databases in Chinese. SRs of CHM for CHD were included. Besides evaluating and summarizing the outcome measures, we also estimated the quality of the included reviews by PRISMA (preferred reporting items for systematic reviews and meta-analyses). Data were extracted according to predefined inclusion criteria by two independent reviewers. Results. 46 articles were included. 20 kinds of CHM were reviewed. 7 SRs were concerned with myocardial infarction (MI), 38 SRs were related to angina pectoris. 11 SRs had primary endpoints, while others focused on secondary endpoints to evaluate CHM for CHD such as angina pectoris and electrocardiogram (ECG). One SR reported more adverse effects of CHM for CHD and of the SRs analyzed quality of life. Many CHM appeared to have significant effect on improving symptoms, ECG, biomarkers and so on. However, most SRs failed to make a definite conclusion for the effectiveness of CHM in CHD patients due specifically to the poor evidence. And according to PRISMA we found most of the trials in the SRs were of low quality. Conclusion. Primary endpoints were not used widely. The benefits of CHM for CHD need to be confirmed in the future with RCTs of more persuasive primary endpoints and high-quality SRs.</description><identifier>ISSN: 1741-427X</identifier><identifier>EISSN: 1741-4288</identifier><identifier>DOI: 10.1155/2012/927392</identifier><identifier>PMID: 22606207</identifier><language>eng</language><publisher>Cairo, Egypt: Hindawi Publishing Corporation</publisher><subject>Acanthopanax ; Angina ; Angina pectoris ; Bibliographic data bases ; Cardiovascular disease ; Cardiovascular diseases ; Chinese medicine ; Clinical trials ; Coronary artery disease ; Data processing ; EKG ; Evidence-based medicine ; Heart attacks ; Heart diseases ; Herbal medicine ; Medical treatment ; Meta-analysis ; Mortality ; Myocardial infarction ; Quality ; Quality of life ; Review ; Systematic review</subject><ispartof>Evidence-based complementary and alternative medicine, 2012-01, Vol.2012 (2012), p.1-9</ispartof><rights>Copyright © 2012 Jing Luo and Hao Xu.</rights><rights>Copyright © 2012 Jing Luo and Hao Xu. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0</rights><rights>Copyright © 2012 J. Luo and H. Xu. 2012</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c466t-8379fcf979589b40fd3f23bc30fc46f7d8b9734230f331fb010318fc22fff7153</citedby><cites>FETCH-LOGICAL-c466t-8379fcf979589b40fd3f23bc30fc46f7d8b9734230f331fb010318fc22fff7153</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347864/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347864/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22606207$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Chen, Keji</contributor><contributor>Keji Chen</contributor><creatorcontrib>Luo, Jing</creatorcontrib><creatorcontrib>Xu, Hao</creatorcontrib><title>Outcome Measures of Chinese Herbal Medicine for Coronary Heart Disease: An Overview of Systematic Reviews</title><title>Evidence-based complementary and alternative medicine</title><addtitle>Evid Based Complement Alternat Med</addtitle><description>The aim of this overview was to summarize the outcome measures of Chinese herbal medicine (CHM) as the treatment of coronary heart disease (CHD) based on available systematic reviews (SRs), so as to display the current situation and evaluate the potential benefits and advantages of CHM on CHD. Methods. An extensive search included the Cochrane Database of Systematic Reviews, MEDLINE, and 4 databases in Chinese. SRs of CHM for CHD were included. Besides evaluating and summarizing the outcome measures, we also estimated the quality of the included reviews by PRISMA (preferred reporting items for systematic reviews and meta-analyses). Data were extracted according to predefined inclusion criteria by two independent reviewers. Results. 46 articles were included. 20 kinds of CHM were reviewed. 7 SRs were concerned with myocardial infarction (MI), 38 SRs were related to angina pectoris. 11 SRs had primary endpoints, while others focused on secondary endpoints to evaluate CHM for CHD such as angina pectoris and electrocardiogram (ECG). One SR reported more adverse effects of CHM for CHD and of the SRs analyzed quality of life. Many CHM appeared to have significant effect on improving symptoms, ECG, biomarkers and so on. However, most SRs failed to make a definite conclusion for the effectiveness of CHM in CHD patients due specifically to the poor evidence. And according to PRISMA we found most of the trials in the SRs were of low quality. Conclusion. Primary endpoints were not used widely. The benefits of CHM for CHD need to be confirmed in the future with RCTs of more persuasive primary endpoints and high-quality SRs.</description><subject>Acanthopanax</subject><subject>Angina</subject><subject>Angina pectoris</subject><subject>Bibliographic data bases</subject><subject>Cardiovascular disease</subject><subject>Cardiovascular diseases</subject><subject>Chinese medicine</subject><subject>Clinical trials</subject><subject>Coronary artery disease</subject><subject>Data processing</subject><subject>EKG</subject><subject>Evidence-based medicine</subject><subject>Heart attacks</subject><subject>Heart diseases</subject><subject>Herbal medicine</subject><subject>Medical treatment</subject><subject>Meta-analysis</subject><subject>Mortality</subject><subject>Myocardial infarction</subject><subject>Quality</subject><subject>Quality of life</subject><subject>Review</subject><subject>Systematic review</subject><issn>1741-427X</issn><issn>1741-4288</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>RHX</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkdtLHDEYxYNYqt32yWcl4Etp2ZrLzCTxoSDbyxYsC72AbyGT-aKRmYkmMyv-9812dKm-9CnJd345OeEgdEDJB0rL8oQRyk4UE1yxHbRPRUHnBZNyd7sXF3voVUrXhDAlhHiJ9hirSMWI2Ed-NQ42dIC_g0ljhISDw4sr30MCvIRYmzZLjbd5gl2IeBFi6E28z6KJA_7kU74Ip_isx6s1xLWHu43Fz_s0QGcGb_EP2AzTa_TCmTbBm4d1hn5_-fxrsZyfr75-W5ydz21RVcNccqGcdUqoUqq6IK7hjvHacuIy4EQjayV4wfKZc-pqQgmn0lnGnHOClnyGPk6-N2PdQWOhH6Jp9U30XY6tg_H6qdL7K30Z1przQsiqyAZvHwxiuB0hDbrzyULbmh7CmDQltCSqLP-ix8_Q6zDGPn9PM1IRSSTlNFPvJ8rGkFIEtw1Did5UqDcV6qnCTB_9m3_LPnaWgXcTkFtqzJ3_j9vhBOcy8stmC6sMCMX_AKEbrPc</recordid><startdate>20120101</startdate><enddate>20120101</enddate><creator>Luo, Jing</creator><creator>Xu, Hao</creator><general>Hindawi Publishing Corporation</general><general>Hindawi Limited</general><scope>ADJCN</scope><scope>AHFXO</scope><scope>RHU</scope><scope>RHW</scope><scope>RHX</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7T5</scope><scope>7TO</scope><scope>7X7</scope><scope>7XB</scope><scope>88G</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M2M</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20120101</creationdate><title>Outcome Measures of Chinese Herbal Medicine for Coronary Heart Disease: An Overview of Systematic Reviews</title><author>Luo, Jing ; Xu, Hao</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c466t-8379fcf979589b40fd3f23bc30fc46f7d8b9734230f331fb010318fc22fff7153</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Acanthopanax</topic><topic>Angina</topic><topic>Angina pectoris</topic><topic>Bibliographic data bases</topic><topic>Cardiovascular disease</topic><topic>Cardiovascular diseases</topic><topic>Chinese medicine</topic><topic>Clinical trials</topic><topic>Coronary artery disease</topic><topic>Data processing</topic><topic>EKG</topic><topic>Evidence-based medicine</topic><topic>Heart attacks</topic><topic>Heart diseases</topic><topic>Herbal medicine</topic><topic>Medical treatment</topic><topic>Meta-analysis</topic><topic>Mortality</topic><topic>Myocardial infarction</topic><topic>Quality</topic><topic>Quality of life</topic><topic>Review</topic><topic>Systematic review</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Luo, Jing</creatorcontrib><creatorcontrib>Xu, Hao</creatorcontrib><collection>الدوريات العلمية والإحصائية - e-Marefa Academic and Statistical Periodicals</collection><collection>معرفة - المحتوى العربي الأكاديمي المتكامل - e-Marefa Academic Complete</collection><collection>Hindawi Publishing Complete</collection><collection>Hindawi Publishing Subscription Journals</collection><collection>Hindawi Publishing Open Access</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Immunology Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Psychology Database (Alumni)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Evidence-based complementary and alternative medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Luo, Jing</au><au>Xu, Hao</au><au>Chen, Keji</au><au>Keji Chen</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Outcome Measures of Chinese Herbal Medicine for Coronary Heart Disease: An Overview of Systematic Reviews</atitle><jtitle>Evidence-based complementary and alternative medicine</jtitle><addtitle>Evid Based Complement Alternat Med</addtitle><date>2012-01-01</date><risdate>2012</risdate><volume>2012</volume><issue>2012</issue><spage>1</spage><epage>9</epage><pages>1-9</pages><issn>1741-427X</issn><eissn>1741-4288</eissn><abstract>The aim of this overview was to summarize the outcome measures of Chinese herbal medicine (CHM) as the treatment of coronary heart disease (CHD) based on available systematic reviews (SRs), so as to display the current situation and evaluate the potential benefits and advantages of CHM on CHD. Methods. An extensive search included the Cochrane Database of Systematic Reviews, MEDLINE, and 4 databases in Chinese. SRs of CHM for CHD were included. Besides evaluating and summarizing the outcome measures, we also estimated the quality of the included reviews by PRISMA (preferred reporting items for systematic reviews and meta-analyses). Data were extracted according to predefined inclusion criteria by two independent reviewers. Results. 46 articles were included. 20 kinds of CHM were reviewed. 7 SRs were concerned with myocardial infarction (MI), 38 SRs were related to angina pectoris. 11 SRs had primary endpoints, while others focused on secondary endpoints to evaluate CHM for CHD such as angina pectoris and electrocardiogram (ECG). One SR reported more adverse effects of CHM for CHD and of the SRs analyzed quality of life. Many CHM appeared to have significant effect on improving symptoms, ECG, biomarkers and so on. However, most SRs failed to make a definite conclusion for the effectiveness of CHM in CHD patients due specifically to the poor evidence. And according to PRISMA we found most of the trials in the SRs were of low quality. Conclusion. Primary endpoints were not used widely. The benefits of CHM for CHD need to be confirmed in the future with RCTs of more persuasive primary endpoints and high-quality SRs.</abstract><cop>Cairo, Egypt</cop><pub>Hindawi Publishing Corporation</pub><pmid>22606207</pmid><doi>10.1155/2012/927392</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Acanthopanax Angina Angina pectoris Bibliographic data bases Cardiovascular disease Cardiovascular diseases Chinese medicine Clinical trials Coronary artery disease Data processing EKG Evidence-based medicine Heart attacks Heart diseases Herbal medicine Medical treatment Meta-analysis Mortality Myocardial infarction Quality Quality of life Review Systematic review |
| title | Outcome Measures of Chinese Herbal Medicine for Coronary Heart Disease: An Overview of Systematic Reviews |
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