Albumin-Binding Domain Conjugate for Near-Infrared Fluorescence Lymphatic Imaging

Purpose The aim of this study was to develop and characterize a novel peptide imaging agent for noninvasive near-infrared fluorescence imaging of protein transport by the lymphatics. An imaging agent consisting of a cyclic albumin-binding domain (cABD) peptide, with sequence, Arg-Leu-Ile-Glu-Asp-Ile...

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Veröffentlicht in:	Molecular imaging and biology 2012-06, Vol.14 (3), p.301-314
Hauptverfasser:	Davies-Venn, Cynthia A., Angermiller, Bonnie, Wilganowski, Nathaniel, Ghosh, Pradip, Harvey, Barrett R., Wu, Grace, Kwon, Sunkuk, Aldrich, Melissa B., Sevick-Muraca, Eva M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Albumin Albumins - metabolism Animal models Animals Binding Sites Electrophoresis, Polyacrylamide Gel fluorescence spectroscopy Fluorescent Dyes - chemistry Fluorescent Dyes - metabolism Fluorescent Dyes - pharmacokinetics fluorophores Humans I.R. radiation Imaging Indocyanine Green Lymphatic diseases Lymphatic Vessels - anatomy & histology Lymphatic Vessels - metabolism Medicine Medicine & Public Health Mice Mice, Inbred C57BL Optical properties Peptides - chemistry Peptides - metabolism Protein Binding Protein transport Radiology Research Article Spectrometry, Fluorescence - methods Spectroscopy, Near-Infrared - methods
Online-Zugang:	Volltext
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