Yeast Swd2 Is Essential Because of Antagonism between Set1 Histone Methyltransferase Complex and APT (Associated with Pta1) Termination Factor

The Set1 complex (also known as complex associated with Set1 or COMPASS) methylates histone H3 on lysine 4, with different levels of methylation affecting transcription by recruiting various factors to distinct regions of active genes. Neither Set1 nor its associated proteins are essential for viabi...

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Veröffentlicht in:	The Journal of biological chemistry 2012-05, Vol.287 (19), p.15219-15231
Hauptverfasser:	Soares, Luis M., Buratowski, Stephen
Format:	Artikel
Sprache:	eng
Schlagworte:	APT Chromatin Immunoprecipitation COMPASS Gene Regulation Genes, Fungal - genetics Histone Methylation Histone-Lysine N-Methyltransferase - genetics Histone-Lysine N-Methyltransferase - metabolism Histones - metabolism Immunoblotting Methylation Mutation Protein Binding Proton-Translocating ATPases - genetics Proton-Translocating ATPases - metabolism Ribosomal Proteins - genetics Ribosomal Proteins - metabolism RNA Polymerase II RNA Polymerase II CTD RNA Processing Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism snoRNA Termination TFIIE Transcription Initiation Factors Transcription Termination
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