Variation in base-substitution mutation in experimental and natural lineages of Caenorhabditis nematodes

Variation among lineages in the mutation process has the potential to impact diverse biological processes ranging from susceptibilities to genetic disease to the mode and tempo of molecular evolution. The combination of high-throughput DNA sequencing (HTS) with mutation-accumulation (MA) experiments...

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Veröffentlicht in:	Genome biology and evolution 2012-01, Vol.4 (4), p.513-522
Hauptverfasser:	Denver, Dee R, Wilhelm, Larry J, Howe, Dana K, Gafner, Kristin, Dolan, Peter C, Baer, Charles F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Caenorhabditis elegans - classification Caenorhabditis elegans - genetics DNA Mutational Analysis Evolution Evolution, Molecular Genetic Variation Genetics Genome, Helminth Mutation Mutation Rate Phylogeny Point Mutation
Online-Zugang:	Volltext
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