Organogenesis and functional genomics of the endocrine pancreas

Functional genomics, the analysis of the wealth of data produced by genome-wide analyses of gene expression, protein–protein, and protein–DNA interactions, has revolutionized biomedical research. Our ability to determine global gene expression profiles, transcription factor-binding sites, and histon...

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Veröffentlicht in:	Cellular and molecular life sciences : CMLS 2012-07, Vol.69 (13), p.2109-2123
Hauptverfasser:	Bramswig, Nuria C., Kaestner, Klaus H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry Biomedical and Life Sciences Biomedicine Cell Biology Cell Differentiation - physiology Cellular biology Data processing Diabetes mellitus Differentiation DNA microarrays Embryo cells Endoderm Epigenesis, Genetic - genetics Epigenesis, Genetic - physiology Epithelium Foregut Gene expression Gene Expression Regulation, Developmental - genetics Gene Expression Regulation, Developmental - physiology Gene mapping Gene Regulatory Networks - genetics Gene Regulatory Networks - physiology Genomics Genomics - methods Histones Humans Islets of Langerhans - embryology Islets of Langerhans - physiology Life Sciences Mammals Mesenchyme Microarray Analysis - methods Organogenesis Organogenesis - genetics Organogenesis - physiology Pancreas Review Reviews Sequence Analysis, DNA - methods Signal transduction Signal Transduction - genetics Signal Transduction - physiology Stem cells Transcription factors Transcription Factors - metabolism
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