Genome-wide determination of RNA stability reveals hundreds of short-lived noncoding transcripts in mammals

Mammalian genomes produce huge numbers of noncoding RNAs (ncRNAs). However, the functions of most ncRNAs are unclear, and novel techniques that can distinguish functional ncRNAs are needed. Studies of mRNAs have revealed that the half-life of each mRNA is closely related to its physiological functio...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Genome research 2012-05, Vol.22 (5), p.947-956
Hauptverfasser:	Tani, Hidenori, Mizutani, Rena, Salam, Kazi Abdus, Tano, Keiko, Ijiri, Kenichi, Wakamatsu, Ai, Isogai, Takao, Suzuki, Yutaka, Akimitsu, Nobuyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line Cell Proliferation Chromosome Mapping External stimuli Gene Expression Profiling - methods Genomes Half-Life Humans Immunoprecipitation Mammals Method non-coding RNA Retinoic acid RNA Stability RNA, Messenger - metabolism RNA, Untranslated - metabolism Sequence Analysis, RNA Staining and Labeling - methods Uridine - analogs & derivatives Uridine - chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!